Baxter International Inc.

Baxter Healthcare Sa

Baxalta Gmbh

Sterling Winthrop Inc.

Baxter Corporation Englewood

Abbott Laboratories Corporation

Edwards Lifesciences Corporation

Baxter Travenol Laboratories, Inc.

The West Company

Steven C. Jepson

Michael J. Finley

Thomas E. Dudar

Vincent C. Desecki

Michael Minailo

Mark G. Gordon

Thomas Edward Dudar

Steven C Jepson

Michael J Finley

Ying-Cheng Lo

Yuanpang Samuel Ding

Joseph V Ranalletta

Bernd Krause

Mark Edward Pasmore

Vincent C Desecki

Grant Anthony Bomgaars

Michael Joseph Sadowski

Peter L Graham

Anastasios Hristakos

Vince C Desecki

Steve C Jepson

Kyungyoon Min

Brian D Zdeb

James Laird

Algirdas J Bindokas

James P Martucci

Shmuel Sternberg

James S Slepicka

Mark A Stiehl

Ross G Krogh

Richard A Rollins

Lewis E Daniels, Jr

Mark Joseph Doty

William S Hurst

Samuel Ding

Donald Smith

Birendra K Lal

Karl Hans Cazzini

Marc Steven Minkus

Paul J Soltys

Douglas W Reitz

Christine L Rebbeck

Mark G Gordon

William A Conard

Kent Lane Lurvey

Edward F Vander Bush

Rongsheng Lin

Jason J White

Rodrigo A Montanez

Camille Summers

Joseph M Tartaglia

Kurt Attermeier

Robert P Dobbie

Yuan Pang Samuel Ding

Walter A Makaryk

Hong Zhu

Jacob Daniel Rivett

Camille Summer

James C Richardson

David J Shepherd

Michael Tung Kiung Ling

Thomas Yatsko

Mary K Zentz

Sydney Jean Cope

David Andrew Ippolito

David Filiberto Schuck

Jeffrey Clyde Nichols

Brent Noblitt

Kathryn M Button

Mark Louis Thoene

Jerome D Olivas

Brian Young

Steven Clarence Jepson

Joseph Vincent Ranalletta

William Spencer Hurst

James Scott Slepicka

James C Laird

Donald A Smith

Jorge A Delcastillo

A medical product includes a bladder, a filtration device, and a sterile product concentrate. The bladder has a perimeter seal and defining a sterile chamber. The filtration device includes a stem and a filter membrane disposed in line with the stem. The stem extends through the perimeter seal and has an inlet end accessible from outside of the perimeter seal and an outlet end in fluid communication with the sterile chamber. The filter membrane can have a nominal pore size in a range of approximately 0.1 μm to approximately 0.5 μm, wherein the filter membrane is shaped as a hollow fiber with a wall and pores residing in the wall of the fiber. The sterile product concentrate is disposed in the sterile chamber and adapted to be reconstituted by the introduction of a pharmaceutical fluid into the chamber through the filtration device.

Medical product including pre-filled product bag

A sterile solution product bag for lyophilizing includes a bladder, a first stem having a first stem inlet end and a first stem outlet end. The first stem outlet end is fluidly connected to the bladder and the first stem inlet end is adapted to receive a liquid. A first filter is disposed in-line with the first stem and includes a first filter membrane, a first filter open end, and a first filter closed end. The first filter closed end is disposed between the first stem inlet end and the first stem outlet end and the first filter open end is disposed in proximity to the first stem inlet end. A second stem having a second stem inlet end fluidly connected to the bladder and a second stem outlet end adapted to receive a vapor. A second filter is disposed within the second stem and includes a filter membrane.

Terminal sterilization filtration closed lyophilization in a container

A system for reconstituting and sterilizing a concentrate includes a mixing container, a filtration device, and a product bag. The a mixing container has an inlet port and outlet port in fluid communication with a mixing chamber disposed between the inlet port and the outlet port. The mixing chamber is adapted to contain a product concentrate. The filtration device has an inlet and an outlet, the inlet of the filtration device coupled to the outlet port of the mixing container. The filtration device includes a filter membrane with a nominal pore size in a range of approximately 0.1 &#x3bc;m to approximately 0.5 &#x3bc;m. The product bag has an inlet port coupled to the outlet of the filtration device, and has a bladder defining an empty sterile chamber for receiving sterilized and reconstituted product resulting from mixing a diluent with a product concentrate in the mixing chamber to obtain a mixture then introduced through the filtration device to obtain the reconstituted and sterilized product.

Dual container system for product reconstitution

A method of providing a plurality of filled product bags of sterile fluid includes positioning a bag assembly onto a filling machine. The bag assembly includes a tube, a filter assembly, bladders, and stems. A stem is attached to a bladder, forms a fluid passageway, fluidly connects to the tube, and provides fluid communication into the bladders. The method includes fluidly coupling an inlet of the filter assembly to a connection line in fluid communication with a fluid source, and filling the bag assembly with a fluid. Filling the bag assembly includes passing the fluid through the filter assembly, the fluid passageway, and into the bladder. The method includes sealing the fluid passageway at a location between the tube and the bladders. The method includes cutting the stem to form a partially filled product bag having the sealed passageway. The method includes performing an integrity test on the filter assembly.

Method and machine for producing sterile solution product bags

A syringe system includes a syringe and a filtration device connected to the syringe for sterilizing and introducing fluid into the syringe. The syringe includes a syringe barrel having a proximal end defining a barrel opening, a distal end defining a delivery opening, a bore extending between the proximal end and the distal end, and a stopper disposed in the bore of the syringe barrel. The filtration device has an inlet and an outlet coupled in fluid communication with the delivery opening at the distal end of the syringe barrel. The filtration device includes a stem and a filter membrane disposed in line with the stem. The filter membrane optionally has a plurality of pores each with a nominal pore size in a range of approximately 0.1 &#x3bc;m to approximately 0.5 &#x3bc;m such that a pharmaceutical fluid can be introduced as a sterilized pharmaceutical fluid into the bore of the syringe barrel by passing through the filtration device.

Medical syringe system with filtered filling port

A product bag includes a bladder and an elongated filtration device. The bladder includes opposing first and second film layers defining a product chamber. The first and second film layers are sealed together along a perimeter seal extending along at least a portion of a perimeter of the bladder. The elongated filtration device includes a housing, a filtration membrane disposed in the housing, an inlet adapted for receiving a fluid to be filtered, and an outlet in fluid communication with the product chamber. A majority of the elongated filtration device is embedded between the first and second film layers of the perimeter seal of the bladder to provide for a compact form factor.

Filtered product bag with compact form factor

A cleaning device for disinfecting a Luer access device includes a housing and a cleaning material. The housing has an opening and elastomeric sidewalls defining an inner cavity. The elastomeric sidewalls are configured to deform and conform to respective surface features of the Luer access device. The cleaning material is positioned within the inner cavity and carries a disinfectant. The cleaning device is configured to removably engage the Luer access device, and the cleaning material is configured to contact at least a portion of the Luer access device when the cleaning device is engaged with the Luer access device.

Disinfectant caps for Luer access devices

A method of providing filled product bags of sterile and particulate-free fluid includes securing a product bag to one of a plurality of movable cradles, wherein the product bag has a bladder, a stem fluidly connected to an opening of the bladder, and a filter disposed in-line with the stem. After securing the bag, an inlet of the stem is connected to an outlet of a nozzle assembly and at least partially filling the product bag with a fluid through a nozzle of the nozzle assembly to create a filled product bag, wherein filling the product bag includes passing the fluid through the filter and into the bladder. After filling, the stem of the filled product bag is sealed at a location below the filter. The stem is cut at a location above the seal and below the filter. The method including performing an integrity test on the filter, removing the filled product bag from the cradle, and depositing the filled product bag into a first bin for rejected bags if the filter fails the integrity test and a second bin for accepted bags if filter passes the integrity test.

An infusion map system includes a memory storing at least infusion mapping instructions, and a processor that executes the stored instructions. When the processor executes the infusion mapping instructions, the infusion map system performs a displaying function that displays at least a portion of an electronic medical record associated with a patient and a diagramming function that receives the electronic medical record and generates an infusion map showing all intravenous drugs being administered to the patient. For each of the drugs, the infusion map further illustrates a route of administration for the drug. An order administering function performed by the system allows a user to alter the infusion map, and a record updating function of annotating the electronic medical record to correspond to the altered infusion map.

Patient information software system including infusion map

An infusion line management system is provided, including a label generating device receiving prescription information for one or more patient prescriptions, the received information being used to generate, for each of the one or more prescriptions, a label including a master label and one or more sub-labels related to the corresponding prescription; each master label includes at least information related to the prescription and an indicator identifying a particular portion of a patient infusion system to which the prescription should be connected; and the one or more sub-labels each include the indicator, the one or more sub-labels being individually removable from the master label and affixable to locations throughout the patient infusion system.

Infusion line management system

Apparatus and systems are disclosed for improved set-up of multi-ingredient compounders. An improved apparatus includes a manifold and a plurality of valve members disposed for movement relative to different corresponding ones of a plurality of inlet ports of the manifold. The valve members are moveable to open and close a corresponding fluid passageway between the corresponding inlet port and an internal passageway of the manifold. A plurality of caps are locatable on different corresponding ones of the inlet ports, with each of the caps being engageable with the corresponding valve member for co-movement from a locked position at which the cap is restricted from removal to an unlocked position at which the cap is removable, e.g. by manual, axial retraction of the cap. An improved system includes a compounder controller operable to control valve actuators of the compounder so as to sequentially move the valve members and corresponding caps from locked to unlocked positions in a predetermined sequence, thereby reducing the potential for undesired cross-connections.

Apparatus and system for improved set-up of multi-ingredient compounder

An intravenous ('IV') liquid delivery system includes: an IV pump tubing set; a shuttle pump or membrane pump actuator operable with the IV pump tubing set; upstream and downstream valve actuators operable with the IV pump tubing set; the IV pump tubing set including an air removal device; an air detector configured to sense air in the IV pump tubing set; a control unit configured and arranged to (i) open the upstream valve actuator and close the downstream valve actuator to allow the pump actuator to draw liquid into a pump actuation portion of the IV pump tubing set, and (ii) close the upstream valve actuator and open the downstream valve actuator to allow the pump actuator to push liquid out of the pump actuation portion, the system configured to attempt to remove the air via the air removal device while operating the upstream and downstream valve actuators according to (i) and (ii).

Intravenous pumping air management systems and methods

Growing community of inventors

Palatine, IL, United States of America

Thomas Edward Dudar