Xavier University of Louisiana

The Administrators of the Tulane Educational Fund

United States of America, as Represented by the Secretary of Agriculture

The University of Toledo

United States Department of Agriculture

Thomas E Wiese

Matthew E Burow

Stephen M Boue

Guangdi Wang

Quan Jiang

Paul W Erhardt

Thomas E Cleveland

John A McLachlan

Rahul Khupse

Jefferey G Sarver

Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer or tumor growth.

Daidzein analogs as treatment for cancer

Two distinct methods are disclosed and claimed for synthesizing glyceollin I plus glyceollin II as a mixture and as their pure forms. Stereochemical isomers and various synthetic intermediates are also synthesized and claimed for their novel compositions of matter. All compounds and their mixtures are claimed for use in formulations that are useful to treat or prevent cancer, or that have utility as selective estrogen receptor modulators, such formulations including enhanced or medical foods, dietary supplements and ethical pharmaceutical agents.

Methods for synthesizing glycinols, glyceollins I and II, compositions of selected intermediates, and therapeutic uses thereof

Growing community of inventors

New Orleans, LA, United States of America

Thomas E Wiese