Agilent Technologies, Inc.

Hewlett-packard Company

Thomas E Price

Jonathan Michael Frentzel

Gilbert Lemke

Rafael Mulero

William H Wilson

Paul C Dryden

Robert P Rhodes

James W Baker

Sammye Elizabeth Traudt

George P Walsh

Fanny Hauser

Michael D Glaser

Roger A Brown

Jared M Bushey

Ellen F Mason

Thomas M Przybylski

Methods and systems for sensing headspace vial presence are described herein. In one embodiment, a system can include a sample probe, a fluid source in fluid communication with the sample probe, one or more of a pressure sensor and a flow sensor in fluid communication with the sample probe, and a processor configured to: (a) receive a first set of signals from the one or more of the pressure and flow sensors, execute an ejection procedure to remove a sample vial from the sample probe, receive a second set of signals from the one or more of the pressure sensor and the flow sensor during step (b), (d) detect whether the ejection procedure is successful from the first set of signals and the second set of signals, and (e) in response to the detecting, initiate one or more actions selected from the group consisting of: a remediation and an alert.

Methods and systems for sensing headspace vial presence

Headspace sampler

Chromatograph

Apparatus for retaining a sorbent bed without permitting voids to be created and that can be readily handled by automated systems is disclosed. A solid phase extraction apparatus is disclosed that is most preferably comprised of a body that contains a sorbent bed and a cap that forms an axial sliding seal with the body. A sleeve is provided to retain the body and create an outside geometry similar to that of a standard glass vial. The sliding seal permits voids in the sorbent bed to be eliminated by axial compressive sealing forces. In a most preferred embodiment, conical sealing surfaces are provided at each end of the disclosed cartridge to facilitate removal of the cartridge after the axial sealing forces are released. The cap and the body are also provided with surfaces compatible with luer fittings, that provide flexibility and permit the use of the invention with existing fluid flow systems.

Solid phase extraction apparatus

Growing community of inventors

St. Georges, DE, United States of America

Thomas E Price