Saol International Limited

Other

Medtronic, Inc.

Thomas E Keene

Michael C Schmitz

Jianwei Li

Deanna S Lane

Lanchi T Le

Carmen E Snaza

Corinne Dominguez

Ngoc T Lu

Methods for preparing sterilized baclofen solutions include adjusting the pH to below a desired pH, and steam sterilizing the solution with adjusted pH, which results in the solution having the desired pH. Such solutions may also have low concentrations of 4-CPP. Injectable baclofen solutions having greater than 2 mg/mL baclofen include between 5 mM and 25 mM of a phosphate or sulfate species. The solution has an ionic strength equivalent of about 1.5 M NaCl. The present application also provides baclofen formulations for use in treating spasticity, brain injury, cerebral palsy, spinal cord injury, cervical injury, multiple sclerosis, thoracic injury, or withdrawal symptoms.

Baclofen formulations and methods for making same

An eyedrop dispenser is disclosed which includes a plastic squeeze bottle having a dispensing nozzle at one end. A collar overfits the dispenser end of the bottle and carries a pair of cooperating, forwardly extending fingers for eyelid contacting purposes. The fingers terminate forwardly in respective eyelid contactors and one finger is pivotally movable relative to the other to spread the eyelid contactors during the eyedrop dispensing process. The movable finger includes an operator extension which engages the bottle sidewall when the eyelid contactors are separated to squeeze the bottle and dispense the eyedrops.

Eyedrop dispenser with eyelid opening means

Growing community of inventors

Golden Valley, MN, United States of America

Thomas E Keene