Other

Endo Pharmaceuticals Inc.

Fleming & Company, Pharmaceuticals

Par Pharmaceutical, Inc.

Fleming & Company

Thomas E Fleming

Theodore H Feller

Angela Sutterer

Herbert C Mansmann, Jr

The present invention relates generally to vitamin Bnasal spray compositions and methods of using the same in the treatment of vitamin Bdeficiency and various disorders that are related to such deficiency. In particular embodiments, the present invention is directed to treatment methods comprising intranasal administration of a cobalamin composition according to a particular dosing and frequency schedule and to a preservative-free nasal spray composition comprising a cobalamin compound useful in the practice of such treatment methods.

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The present invention relates to the prevention and treatment of atopic dermatitis and treatment of atopic dermatitis and other eczematous disorders by application of topical mast cell stabilizers including cromolyn sodium, nedocromil or lodoxamide, in a vehicle of a buffered isotonic saline solution (OCEAN&reg;).

Treating eczema with a combination of isotonic saline ocean&reg; and nasal mast cell stabilizers

The present invention relates to compositions and methods for the prevention and/or treatment of allergic, autoimmune, septic shock or infectious diseases using magnesium gluconate alone or in combination with one or more antioxidants or an antiinflammatory agent. The invention also relates to the inhibition of production of inappropriate levels of lipid mediators and cytokines.

Methods and compositions for the prevention and treatment of

The present invention relates to methods and compositions for the prevention and/or treatment of exercise-induced muscle cramps, stiffness, pain or spasms, using magnesium gluconate alone or in combination with one or more antioxidants or conventional pharmacologic therapy. The invention also relates to inhibition of production of oxygenated molecules, oxygen free radicals and lipid peroxidation.

Methods and compositions for the prevention and treatment of muscle

The present invention relates to methods and compositions for the prevention and/or treatment of diabetes mellitus, using magnesium gluconate alone or in combination with one or more antioxidants or conventional diet and/or insulin therapy. The invention also relates to inhibition of production of oxygen free radicals and lipid peroxidation.

Methods and compositions for the prevention and treatment of diabetes

A tool, for placement of predetermined amounts of granular fertilizer into the soil in a consolidated mass, provides an elongate body with a handle structure in its upper portion and a tubular fertilizer reservoir in its lower portion. The fertilizer reservoir defines an open upper portion for filling and slidably carries an associated tube for adjustment of the volume of a fertilizer charge. An angulated bottom portion of the reservoir allows insertion into the earth and carries a pivotally articulated cover to allow opening of the bottom portion of the reservoir for dispersement of a fertilizer charge. The lower medial portion of the tool body provides a pivotally mounted foot support to aid insertion of the fertilizer reservoir into the earth. Dispersement structure communicates from the pivotally articulated reservoir cover to the handle structure for opening of the cover from the handle area for dispersement of fertilizer.

Tool for placement of amassed granular fertilizer in soil

A tool to releasably engage in a channel of a concrete block for lifting provides an elongate body rod defining a fastening loop in its upper portion and carrying in its lower portion two radially extending fins having an obtuse central angle less than a straight angle therebetween. Each fin pivotally supports vertically spaced, parallel connector links that pivotally interconnect vertically orientated fastening arms for similar radial motion. The body provides at least one fixed fastening arm extending on a line bisecting the central angle between the two fins. Release mechanism provides a release collar slidable on the body between the fins and fastening ring. The collar pivotally carries connector links that interconnect with the upper fastening arms to radially move the fastening arm responsive to collar motion. A compression spring carried about the body rod between the collar and the fastening ring biases the collar downwardly and responsively the fastening arms outwardly. The biasing force is related to the tool weight so that in relaxed condition the fastening arms interconnect within a block channel, but when the tool is lifted by the release collar the fastening arms move to release interconnection within a block channel.

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St. Louis, MO, United States of America

Thomas E Fleming