Societe De Conseils De Recherches Et D'applications Scientifiques Sas

Other

Societe De Conseils De Recherches Et D'applications Scientifiques (s.c.r.a.s.)

Ipsen Pharma S.a.s.

Abbott Laboratories Corporation

Abbvie Inc.

Sanofi Pharmaceuticals, Inc.

Production Solutions, Inc.

Soci&eacute;t&eacute; De Conseils De Recherches Et D'applications Scientifiques, S.a.s.

Thomas D Gordon

Barry A Morgan

Christophe Thurieau

Lydie Francine Poitout

Marie-Odile Galcera

Kevin Patrick Cusack

Christophe Philippe Moinet

Douglas T Farlow

Martin E Hayes

Dennis C H Bigg

Marie-Odile Lonchampt

Michael M Friedman

Grégoire Prevost

Kelly Mullen

Andrew Burchat

Grier A Wallace

David Ihle

Lei Wang

Gloria Y Lo Schiavo

Anna M Ericsson

Lawrence I Kruse

Kristine E Frank

Richard W Dixon

Adrian Hobson

David J Calderwood

Michael DeWitt Culler

Kirill A Lukin

Michael Z Hoemann

Jacques Pommier

Michael Morytko

Christophe Moinet

Maria A Argiriadi

Neil Wishart

Teruna J Siahaan

Eric C Breinlinger

David Wayne Borhani

Biqin C Li

Lu Wang

Dilinie P Fernando

Robert V Talanian

Mark A Ator

Graham K Ansell

Xiaoyun Wu

Gagandeep K Somal

Shannon R Fix-Stenzel

Claude E Barberis

Pintipa Grongsaard

Bin Li

Xiaolei Zhang

Lily K Abbott

Wouter Iwema Bakker

Gr&eacute;goire Prevost

James Arthur Gainor

Barry Arnold Morgan

Kelly D Mullen

David W Borhani

Lu X Wang

The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

Heterocyclic nuclear hormone receptor modulators

The present invention is directed to novel, potent, and selective agents, which are agonists or antagonists of the one or more of the individual receptors of the S1P receptor family. The compounds of the invention are useful as therapeutics for treating medical conditions associated with agonism or antagonism of the individual receptors of the S1P receptor family.

Sphingosine-1-phosphate receptor agonist and antagonist compounds

Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I) wherein the substituents are as defined herein, which are useful as therapeutic agents.

Indazole compounds

The present invention discloses processes for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates.

Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates

A family of imidazole compounds useful for inhibiting the activity of prenyl transferases. The compounds are covered by the following formula: wherein X is (CHR)(CH)Z(CH)where Z is O, N(R), S, or a bond; Y is CO, CH, CS, or a bond; Ris or N(RR); and the remaining substituents are as defined in the disclosure.

Prenyl transferase inhibitors

A system comprising at least one liquid detector that has a cathode and an anode and at least one switching mechanism for receiving a positive voltage from the cathode and anode of a liquid detector. Each switching mechanism comprises at least one switching component that is connected with a power source. Each switching component supplying a current from its connected power source when the switching component is activated. Preferably, each switching component is activated, when the switching component receives a voltage that exceeds a threshold voltage. The system also comprises a base unit that communicates remotely or through direct connection with each switching mechanism. The base unit communicates with at least one application control device that is connected with at least one electronic control apparatus for preventing the undesirable condition. The base unit may also be connected with at least one notification control device that is connected with an electronic notification apparatus for notifying a user that the undesirable condition has been detected. The electronic notification apparatus may comprise a visible light or LED and/or an alarm.

System for detecting an undesirable condition and manipulating an electronic device

The present invention is directed to imidazolyl derivatives of formula (I) where the substituents are defined in the specification, which are useful as agonist or antagonists of somatostatin receptors.

Imidazolyl derivatives

The present invention is directed to imidazolyl derivatives of formula (I) where the substituents are defined in the specification, which are useful as agonists or antagonists of somatostatin receptors. 

A family of compounds capable of inhibiting the activity of farnesyl transferase.

Farnesyl transferase inhibitors

The present invention is directed to compounds of the formula wherein the variables are as defined in the specification. The compounds are useful for inhibiting farnesyl transferase and for the treatment of tumors and restenosis.

An improved substrate support system for clamping spring loaded pins that support substrates, such as printed circuit boards, which have even profiles, and uneven profiles due to components being installed on one side during manufacturing operations to the opposite side of the substrate. The substrate support system can utilize a cam lever, a knob, or a draw latch to move a clamping plate between an aligned position and a clamping position.

Substrate support system

The present invention is directed to imidazolyl derivatives or pharmaceutically acceptable salts thereof which are useful as agonists or antagonists of somatostatin receptors, having the following formula (I), wherein the substituents are defined in the specification.

Claimed is a somatostatin agonist according to formula (I),D-Phe-c(Cys-Tyr(I)-D-Trp-Lys-Val-Cys)-Thr-NH, &#x2003;&#x2003;(I)or a pharmaceutically acceptable salt thereof, and uses thereof.

Somatostatin analog and uses thereof

Growing community of inventors

Medway, MA, United States of America

Thomas D Gordon