Pall Corporation

Thomas C Gsell

David B Pall

Vlado I Matkovich

Thomas J Bormann

Peter J Degen

Frank R Pascale

Isaac Rothman

Brian T Muellers

Irving B Joffee

Colin F Harwood

Tony Alex

Richard F Salinaro

Michael R Gildersleeve

Isaak Vasserman

Eric J Krasnoff

Gerard R DelGiacco

Warren M Foss

Jeffrey K Chambers

Keith S Morris

Randy Garcez

Harvey Brandwein

Stanley W Kidd

Donald B Stevens, Sr

Jeffrey M Seibert

Barry J Weissman

Charles P Lipari

Duane Piechocki

Eleni C Yanakis

Luis Rios

Paul C Smith, Iii

Gerard R Del Giacco

M JoAnna Abes

Leonard R Castellano

The present invention provides integral porous membranes comprising an amorphous halopolymer, as well as processes for preparing the membranes, and devices comprising the membranes. An example of an amorphous halopolymer is a copolymer of tetrafluoroethylene and perfluoro-2,2-dimethyl-1,3-dioxole.

Porous membrane

Devices, systems and methods for treating a biological fluid are provided comprising placing the fluid in contact with a complement filter capable of depleting at least one complement fragment from the fluid while at least one component of the biological fluid is being stored.

Biological fluid treatment system and method

A method for processing a biological fluid comprises the steps of collecting platelet-rich plasma (PRP) in a container containing a complement filter, centrifuging the PRP in the container to provide a supernatant layer comprising a volume of platelet-poor plasma (PPP) and a sediment layer including concentrated platelets, passing most of the volume of the PPP from the container, suspending the platelets in the remaining volume of PPP to provide a platelet suspension and storing the platelet suspension in the container for a storage period of at least about 24 hours while contacting the complement filter with at least a portion of the platelet suspension and removing complement from the platelet suspension.

Method for processing a biological fluid

A method for automatically processing a biological fluid is disclosed. The method includes the steps of obtaining a container having a biological fluid therein, providing a first signal and communicating with an automated control arrangement to establish flow of at least a portion of the biological fluid along a fluid flow path through a leukocyte depletion medium, providing a second signal and communicating with the automatic control arrangement to terminate flow along the fluid flow path wherein providing the second signal includes sensing the back pressure in the fluid flow path or the flow rate through the leukocyte depletion medium.

Automated method for processing biological fluid

A vibratory separation system having a drive mechanism for imparting a vibratory motion to a membrane module to enhance filtration. The membrane module comprises one or more filter elements secured to one another, each having a permeable membrane. The vibratory motion imparted to the membrane module generates a dynamic flow boundary layer at the permeable membranes. This fluid shear boundary layer, in turn, generates lift, thereby inhibiting fouling of the membranes.

Vibratory separation systems and membrane separation units

The present invention provides a method of preparing polyarylene sulfide fibers, particularly polyphenylene sulfide fibers, comprising melt blowing a blend of polyarylene sulfide and a polyolefin, wherein the polyolefin is present in the blend in an amount of up to about 40% by weight of the total blend. The present invention also provides fibers, webs, and other products prepared in accordance with the present inventive method.

Polyarylene sulfide resin composition

Polyarylene sulfide melt blown fibers and products

An automated system for processing biological fluid includes a pressure differential generator, a biological fluid processing assembly, and an automated control arrangement coupled to at least one of the pressure differential generator and the biological fluid processing assembly. The automated system may include a porous medium, such as a red cell barrier medium, a leukocyte depletion medium, or a combination red cell barrier/leukocyte depletion medium. The automated system may also include a sensor producing a signal reflecting a parameter of fluid flow.

Automated system and method for processing biological fluid

The present invention provides a supported membrane assembly comprising a membrane adhered to a support material by way of a nonwoven web of multicomponent fibers therebetween, wherein the multicomponent fibers comprise a first polymer and a second polymer such that the second polymer is present on at least a portion of the surface of the multicomponent fibers and has a softening temperature below the softening temperatures of the first polymer, the membrane, and the support material, and the supported membrane assembly has a water flow rate at least about 20% of the water flow rate of the membrane alone. The present invention also provides a filter element comprising a housing and such a supported membrane assembly, as well as a method of preparing such a supported membrane assembly and methods of using such a supported membrane assembly.

Dynamic supported membrane assembly and method of making and using it

Leucocyte depletion filter assemblies decrease the leucocyte content of a leucocyte-containing liquid at a flow rate of greater than about 25 milliliters per minute. These filter assemblies are suitable for use in an extracorporeal circuit. Methods for removing leucocytes and other deleterious matter are also disclosed.

Leucocyte depleting filter device and method of use

The present invention provides for processing a biological fluid such as blood, to separate at least one component from the biological fluid, and to remove leukocytes from the separated component while returning the component depleted biological fluid to the source of the fluid. Illustratively, blood is obtained from a source such as a donor, and platelets are separated from the bold. Gas is separated from the flow path of the separated platelets, which are depleted of leukocytes, while platelet depleted blood is returned to the donor.

Method for separating components from a biological fluid

The present invention provides a filtration method comprising passing a protein-containing solution through a filtration medium comprising a polyamide-polyether copolymer, such as a polyamide/polyalkylene-oxide-diamine, particularly a nylon 6/polyethylene-oxide-diamine copolymer.

Method of filtering a protein-containing fluid

A system for processing a biological fluid by spirally passing the biological fluid along at least one first flow path along the first surface of a separation medium in a separation device is disclosed. Also disclosed is a system for processing a biological fluid utilizing a plurality of pressure differential generators including enclosed chambers.

Device and method for separating components from a biological fluid

Automated system for processing biological fluid

Polyarylene sulfide melt blowing methods and products

Growing community of inventors

Glen Cove, NY, United States of America

Thomas C Gsell