Basf Aktiengesellschaft

Thomas Bogenst&auml;tter

Knut Kessel

G&uuml;nter Scherr

Michael Kluge

Thomas Greindl

Norbert Biedermann

Alfred Oftring

Gunther Berndl

Gregor Brodt

Norbert Wagner

J&ouml;rg Breitenbach

Elisabeth Kappes

Christian Ott

Dirk Franke

Stefan Orsten

S&ouml;ren Hildebrandt

Wolfgang H&auml;hnlein

Rudi Kr&ouml;ner

A process for the preparation of creatine or creatine monohydrate by reaction of sodium or potassium sarcosinate with cyanamide at a temperature from 20 to 150&deg; C. and a pH from 7.0 to 14.0 comprises carrying out the pH adjustment with carbonic acid.

Process for the preparation of creatine or creatine monohydrate

Process for producing solid creatine dosage forms and dosage forms obtainable thereby

A process for preparing guanidine derivatives, in particular creatine, is described and entails continuously combining a cyanamide derivative and a primary or secondary amine in the presence of crystals of the guanidine derivative.

Process for preparing guanidine derivatives

Described is a process for preparing 1-(2-sulfoethyl)pyridinium betaine wherein pyridine is reacted with a sulfoethylating agent from the group consisting of carbyl sulfate, ethionic acid and its salt and vinylsulfonic acid and vinylsulfonate, the reaction taking place in aqueous solution or in pyridine.

Synthesis of 1-(2-sulfoethyl)-pyridinium betaine

A process for purifying creatine is described in which the creatine to be purified in the form free of water of crystallization is introduced into a saturated aqueous solution of creatine monohydrate, in which the creatine free of water of crystallization is dissolved with hydration, crystals of creatine monohydrate precipitate from the aqueous solution and these are separated off from the aqueous solution.

Process for purifying creatine

A process for preparing vicinal diols or polyols from an organic reaction mixture containing formic esters of vicinal diols or polyols, in which water is added to the reaction mixture, without addition of bases, and the formic esters are hydrolyzed in a subsequent thermal treatment, the aqueous formic acid is removed, and vicinal diols or polyols remain behind.

Method for producing vicinal diols or polyols

A process for the preparation of an O-alkylisourea of the formula I,

Preparation on an O-alkylisourea

Growing community of inventors

Bad Dürkheim, Germany

Thomas Bogenstätter

Growing community of inventors

Bad Dürkheim, Germany

Thomas Bogenst&auml;tter

Thomas Bogenstätter