Evonik Operations Gmbh

Thomas Bekel

Georg Thierbach

Frank Schneider

Kornelia Voss

Kornelia Voß

Kornelia Voβ

Fermentative production of L-lysine using an L-lysine excreting bacterium of the specieshaving a completely or partly deleted whiB4 gene is provided.

Method for the fermentative production of L-lysine using an L-lysine excreting bacterium of the specieshaving a completely or partly deleted WHIB4 gene

A bacterium of the specieshas the ability to excrete L-lysine, and contains in its chromosome a polynucleotide encoding a mutated polypeptide having the assumed function of an acyltransferase, hydrolase, alpha/beta hydrolase or of a pimeloyl-ACP methyl ester esterase. Also, a method is used for producing L-lysine using such bacterium.

Method for the fermentative production of L-lysine

A method is useful for the fermentative production of L-lysine using astrain having a mutated Kup transporter.

Method for the fermentative production of L-lysine usingstrains with a mutated kup transporter

A method is used for the fermentative production of L-lysine using bacteria of the species, having the ability to excrete L-lysine and containing in their chromosome a mutated NCgl2816 polynucleotide. Further, the method is used for cultivating the bacteria in a suitable medium under suitable conditions, and accumulating said L-lysine in the suitable medium to form an L-lysine containing fermentation broth.

Method for the fermentative production of L-lysine by modified

The present invention provides a bacterium of the genus, in particular of the species, having the ability to excrete an L-amino acid selected from proteinogenic L-amino acids and L-omithine and new measures for the fermentative production of proteinogenic L-amino acids and L-ornithine by such bacteria.

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Halle, Germany

Thomas Bekel