Medtronic, Inc.

Livanova Usa, Inc.

Cyberonics, Inc.

Apnex Medical, Inc.

Other

Cardiovascular Systems, Inc.

Thomas Barry Hoegh

Stephen L Bolea

Robert E Atkinson

Bruce J Persson

Carl D Wahlstrand

James M Olsen

Sidney F Hauschild

Gregory Anthony Hrdlicka

Wondimeneh Tesfayesus

Brian D Kuhnley

John P Beck

Scott Thomas Mazar

Paula M Kaplan

Dale G Suilmann

Adam K Hoyhtya

Thomas E Cross, Jr

Keith E Jasperson

Daniel A Parrish

Christopher K Thorp

Jason Skubitz

Peter R Eastwood

David R Hillman

Mark R Bosshard

Timothy Harold Grafe

Joseph P Higgins

Matthew Wayne Tilstra

Matthew D Cambronne

Richard Carlton Mattison

Victor Leo Schoenle

Robert Edward Kohler

Kayla J Eichers

Matthew Saterbak

Michael J Grace

James M Olson

Kayla Eichers

Robert E Kohler

Carl A Wahlstrand

Devices, systems and methods of neurostimulation for treating obstructive sleep apnea. The system is adapted to send an electrical signal from an implanted neurostimulator through a stimulation lead to a patient's nerve at an appropriate phase of the respiratory cycle based on input from a respiration sensing lead. External components are adapted for wireless communication with the neurostimulator. The neurostimulator is adapted to deliver therapeutic stimulation based on inputs.

Obstructive sleep apnea treatment devices, systems and methods

A stimulation system for delivery of a stimulation signal to a hypoglossal nerve of a patient to treat obstructive sleep apnea. The stimulation system includes an implantable receiver coil configured to be implanted under a mandible of the patient; a nerve electrode coupled to the implantable receiver coil, the nerve electrode configured to deliver the stimulation signal to the hypoglossal nerve of the patient; an external pulse generator configured to generate the stimulation signal; and an external transmitter coil configured to wirelessly transmit the stimulation signal from the external pulse generator to the implantable receiver coil, the external transmitter coil being carried by an adhesive patch configured to be placed on the skin adjacent the implantable receiver coil under the mandible of the patient.

An implantable neurostimulation system comprises a stimulation delivery lead and a neurostimulator. The stimulation delivery lead is coupled to an electrode. The neurostimulator is adapted to deliver a neurostimulation signal to the subject and comprises a microprocessor. The microprocessor is programmed to identify a stimulation operating window for the therapy including a first threshold and a second threshold. The second threshold comprises an awake level and an asleep level. Identifying the stimulation operating window comprises titrating a stimulation setting of the neurostimulator while the subject is awake until the first threshold and the awake level of the second threshold are identified. Identifying the stimulation operating window further comprises subsequently repeating the step of titrating the stimulation setting of the neurostimulator while the subject is asleep until the asleep level of the second threshold is identified.

Embodiments include a screening method for evaluating patient suitability for an implanted hypoglossal nerve stimulation (HGNS) device. The screening method evaluates blood oxygen data relating to respiratory events, with the blood oxygen data providing mean blood oxygen desaturation values for comparison to severity thresholds to identify patients who are likely or unlikely to benefit from the implantation of the HGNS device.

Obstructive sleep apnea treatment screening methods

Devices and methods for improving the coupling between the soft palate and the genioglossus. This may be accomplished, for example, but shortening or stiffening the palatoglossal arch. Improved coupling between the soft palate and the genioglossus may be beneficial to a patient suffering from obstructive sleep apnea (OSA) as a stand-alone procedure, or in combination procedures and devices that cause anterior displacement of the tongue such as hypoglossal nerve stimulation, genioglossus advancement surgery, mandibular advancement surgery, mandibular advancement (oral) appliances, etc.

Devices and methods for sleep apnea treatment

Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.

Devices, systems and methods for nerve stimulation for OSA therapy.

In one embodiment, a method for maintaining patency of an upper airway of a patient to treat obstructive sleep apnea may include delivering an electrical stimulation to a portion of a superior laryngeal nerve via a nerve cuff when the nerve cuff is adjacent an external surface of the superior laryngeal nerve, the nerve cuff having a plurality of electrodes, wherein the nerve cuff is configured to be connected to an electrical stimulator via a stimulation lead.

A method including chronically implanting a nerve cuff electrode on a portion of a hypoglossal nerve, chronically implanting a respiration sensing lead subcutaneously in a thorax of a patient, the respiration sensing lead having a plurality of bio-impedance electrodes defining at least one bio-impedance vector. The method may also include sensing a bio-impedance signal corresponding to respiration via a bio-impedance vector on an anterior side of the thorax, analyzing the bio-impedance signal to identify onsets of expiration, predicting an onset of a future expiratory phase, and delivering a stimulus to the portion of the hypoglossal nerve via the nerve cuff electrode, wherein the stimulus is delivered as a function of the bio-impedance signal; wherein stimulus delivery is initiated before the onset of the future expiratory phase and continued during an entire inspiratory phase, and wherein the method is performed without identifying an onset of an inspiratory phase.

A medical lead is configured to be implanted into a patient's body and comprises a lead body, and an electrode coupled to the lead body. The electrode comprises a first section configured to contact the patient's body, and a second section capacitively coupled to the first section and configured to be electrically coupled to the patient's body.

Lead electrode for use in an MRI-safe implantable medical device

The present system is directed in various embodiments to methods, devices and systems for sensing, measuring and evaluating compliance in a bodily conduit. In other embodiments, the methods, devices and systems sense, measure, determine, display and/or interpret compliance in a bodily conduit and/or a lesion within the bodily conduit. In all embodiments, the sensing, measuring, determining, displaying and/or interpreting may occur before, during and/or after a procedure performed within the bodily conduit. An exemplary conduit comprises a blood vessel and an exemplary procedure comprises a vascular procedure such as atherectomy, angioplasty, stent placement and/or biovascular scaffolding.

Methods, devices and systems for sensing, measuring and/or characterizing vessel and/or lesion compliance and/or elastance changes during vascular procedures

Growing community of inventors

Edina, MN, United States of America

Thomas Barry Hoegh