Schering Aktiengesellschaft

Thomas Balzer

Ulrich Speck

Werner Krause

Andreas Muhler

Wolf-Rudiger Press

Franz-Karl Maier

Michael Bauer

Gabriele Schuhmann-Giampieri

Gabriele Schuhmann-Giampiere

The invention relates to new, multiply substituted diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, that contain an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents that contain these compounds, their use as contrast media and antidotes, and process for the production of pharmaceutical agents.

Multiply substituted DTPA derivatives and their metal complexes, and

The disclosed metal complexes are suitable as contrast media for computer tomography of the liver and the biliary tracts.

Use of tetra azacycle complexes as x-ray diagnostic agents for the liver

The invention relates to new diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, that contain an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents that contain these compounds and their use as contrast media and antidotes.

DTPA derivatives substituted in a novel way, their metal complexes, and

Metal complexes containing a metal of atomic numbers 39-42, 44-51 or 56-83 and a complexing agent can be used for the production of contrast media for use in the contrast-enhanced computer tomography of the liver and the biliary tracts.

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Berlin, Germany

Thomas Balzer