Dexcom, Inc.

Abbott Diabetes Care Inc.

Other

Insulet Corporation

Glumetrics, Inc.

Medtronic Minimed, Inc.

University of California

Minimed, Inc.

Biolinq Incorporated

Thomas Arnold Peyser

Apurv Ullas Kamath

Peter C Simpson

Aarthi Mahalingam

Arturo Garcia

Stephen J Vanslyke

Daiting Rong

Michael J Estes

Adam Heller

Marc Barry Taub

Naresh Chandra Bhavaraju

Sebastian Böhm

Sebastian Bohm

Jack Pryor

Leif N Bowman

Paul V Neale

Jacob S Leach

Matthew D Wightlin

Shawn Larvenz

Mark Dervaes

Andrew Attila Pal

Anna Leigh Davis

Michael Robert Mensinger

Hari Hampapuram

John Joseph Mastrototaro

William P Van Antwerp

Joe H Satcher, Jr

Phil Mayou

Jason B O'Connor

Yibin Zheng

Joon Bok Lee

Jorge Valdes

Timothy Christian Dunn

John Charles Mazza

Geoffrey V McGarraugh

R Curtis Jennewine

Benjamin J Feldman

Gary Alan Hayter

Mark Kent Sloan

Udo Hoss

Kenneth J Doniger

Phillip Yee

Gary Ashley Stafford

Michael R Love

Wesley Scott Harper

David Michael Morelock

Glenn Howard Berman

Russell O Potts

Richard Chien Yang

Anna Leigh Rack-Gomer

Jolyon Robert Bugler

Disha B Sheth

Phong Lieu

Tom Miller

Kenneth San Vicente

Eric Johnson

Mohammad Ali Shariati

Soya Gamsey

Lucas Bohnett

Dmytro Sokolovsky

David R Markle

David Price

Thomas Hall

Stephen M Lane

Trang Ly

Jennifer Lena Schneider

Kevin Sayer

Murrad Kazalbash

Kerstin Rebrin

Matthew A Romey

Christopher B Darrow

Jennifer Harder

Andrew H Naegeli

Joshua Ray Windmiller

Annie C Tan

Herbert L Berman

David J Vachon

Timothy T Goodnow

Ritchie A Wessling

Glenn Noronha

Daniel H Lee

Jared Rylan Tangney

Jeff T Suri

Jason O'connor

Alan Steven Campbell

Sirilak Sattayasamitsathit

Roy E Morgan

Aaron M Heiss

Joseph C Walsh

James W Moyer

Pradnya Prakash Samant

Eric Patterson

Michael A Pani

Mikhail A Kouchnir

Buddhadev Paul Chaudhuri

Geoffrey V Mcgarraugh

Michael Pani

Curtis Jennewine

Evan L Hsu

William C Hsu

Methods and Devices to monitor the level of at least one analyte are provided.

Analyte monitoring and management device and method to analyze the frequency of user interaction with the device

The present invention relates generally to systems and methods for processing, transmitting, and displaying data received from continuous analyte sensor, such as a glucose sensor. In some embodiments, the continuous analyte sensor system comprises a sensor electronics module that includes power saving features. One feature includes a low power measurement circuit that can be switched between a measurement mode and a low power mode, in which charging circuitry continues to apply power to electrodes of a sensor during the low power mode. In addition, the sensor electronics module can be switched between in a low power storage mode higher power operational mode via a switch. The switch can include a reed switch or optical switch, for example. A validation routine can also be implemented to ensure an interrupt signal sent from the switch is valid. The continuous analyte sensor can be physically connected to a sensor electronics module, which is in direct wireless communication with a plurality of different display devices.

Advanced continuous analyte monitoring system

Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, a controller module, and optionally a single point glucose monitor are provided. Integration may be manual, semi-automated and/or fully automated.

Time averaged basal rate optimizer

Disclosed are a system, methods and computer-readable medium products that provide safety constraints for an insulin-delivery management program. Various examples provide safety constraints for a control algorithm-based drug delivery system that provides automatic delivery of a drug based on sensor input. Glucose measurement values may be received at regular time intervals from a sensor. A processor may predict future glucose values based on prior glucose measurement values. The safety constraints assist in safe operation of the drug delivery system during various operational scenarios. In some examples, predicted future glucose values may be used to implement safety constraints that mitigate under-delivery or over-delivery of the drug while not overly burdening the user of the drug delivery system and without sacrificing performance of the drug delivery system. Other safety constraints are also disclosed.

Safety constraints for a control algorithm based drug delivery system

Systems and methods for applying time-dependent algorithmic compensation functions to data output from a continuous analyte sensor. Some embodiments determine a time since sensor implantation and/or whether a newly initialized sensor has been used previously.

Systems and methods for processing analyte sensor data

Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

Fault discrimination and responsive processing based on data and context

Described herein are variations of an analyte monitoring system, including an analyte monitoring device. For example, an analyte monitoring device may include an implantable microneedle array for use in measuring one or more analytes (e.g., glucose), such as in a continuous manner. The microneedle array may include, for example, at least one microneedle including a tapered distal portion having an insulated distal apex, and an electrode on a surface of the tapered distal portion located proximal to the insulated distal apex. At least some of the microneedles may be electrically isolated such that one or more electrodes is individually addressable.

Continuous analyte monitoring system with microneedle array

Methods and apparatus, including computer program products, are provided for processing analyte data. In some example implementations, a method may include generating glucose sensor data indicative of a host's glucose concentration using a glucose sensor; calculating a glycemic variability index (GVI) value based on the glucose sensor data; and providing output to a user responsive to the calculated glycemic variability index value. The GVI may be a ratio of a length of a line representative of the sensor data and an ideal length of the line. Related systems, methods, and articles of manufacture are also disclosed.

Systems and methods for managing glycemic variability

An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.

Analyte monitoring device and methods of use

Growing community of inventors

Menlo Park, CA, United States of America

Thomas Arnold Peyser