Arzneimittelwerk Dresden Gmbh

Thomas Arnold

Hans-Joachim Lankau

Klaus Unverferth

Reni Bartsch

Angelika Rostock

Christine Tober

Chris Rundfeldt

Manfred Menzer

Vladimir G Granik

Sofia Grizik

Abgelika Rostock

The invention relates to 1,5-dihydropyrrol-2-ones of Formula 1 which contain an aryl radical in the 1-position and a secondary amine radical in the 4-position, to a process for making and for a process to treat various forms of epilepsies and of states of anxiety and tension.

4-amino-1-aryl-1,5-dihydropyrrol-2-ones and process for making

Antiepileptic compounds of the formula ##STR1## wherein X is hydrogen, a C.sub.1-4 alkyl, C.sub.1-4 alkoxy, trifluoromethyl, trifluoromethoxy or halogen residue, A is an amino, C.sub.1-4 alkylamino, C.sub.1-4 dialkylamino, morpholino, piperidino or pyrrolidino residue, and n is a cardinal number from 0 to 5, and process for preparing the foregoing compounds and for their use as anticonvulsives.

4-amino-1-arylpyridin-2-ones and process for making

The invention relates to pyrazolo[3,4d]pyrimidin-4(5H)-ones and pyrazolo[3,4-d]pyrimidine-4(5H)-thiones and their tautomers and pharmaceutically acceptable salts, which contain a benzyl radical in the 2-position, processes for their preparation and their use as medicaments, in particular for the treatment of epilepsies of various forms and of allergic/asthmatic diseases.

Anticonvulsive and antiallergic/antiasthmatic

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Radebeul, Germany

Thomas Arnold