Warsaw Orthopedic, Inc.

Thomas Andrew Simonton

Sean M Haddock

Susan J Drapeau

William F McKay

Hai H Trieu

Jeffrey Mendel Gross

John Myers Zanella

Lehmann K Li

Jeffrey L Scifert

Vanja Margareta King

Keith Matthew Kinnane

A drug cartridge is provided for delivering a drug pellet to a site beneath the skin of a patient, the drug cartridge comprising: two or more chambers, each chamber holding a drug pellet and having a proximal end and a distal end, the proximal end of the chamber having an opening to receive the drug pellet and a plunger, the distal end of the chamber having an opening for receiving the plunger and passage of the drug pellet, a bulking agent disposed within at least a portion of each chamber, wherein movement of the plunger to an extended position moves the drug pellet within the chamber of the cartridge out the distal end of the chamber and out of the drug cartridge. In some embodiments, instead or with the bulking agent pierceable superior and inferior covers are used to contain the drug pellets.

Drug cartridge for delivering a drug depot comprising a bulking agent and/or cover

The invention relates to a bioactive settable hydrogel matrix having a pore creating material, which may also carry a therapeutic agent, and methods of using the same, for example, use in promoting internal wound healing, tissue repair, tissue regeneration.

Tissue augmentation with active agent for wound healing

Effective methods of treating back pain from an intervertebral disc are provided. The methods of treatment include administering an immediate release analgesic at or near the intervertebral disc; administering a bulking agent or sealing agent within the intervertebral disc; and administering a sustained release analgesic within the intervertebral disc, wherein the sustained release analgesic releases the analgesic over a period of at least one day.

Methods for treating an intervertebral disc using local analgesics

Effective compositions and methods for treating an intervertebral disc are provided. The compositions and methods comprise a bulking agent or sealing agent, the bulking agent or sealing agent adapted to be administered at or within the intervertebral disc, the bulking or sealing agent having a drug depot comprising an effective amount of a therapeutic agent disposed therein, wherein the drug depot is capable of releasing an effective amount of the therapeutic agent over a period of at least one day.

Compositions and methods for treating an intervertebral disc using bulking agents or sealing agents

Drug depot delivery devices and methods are provided for delivering one or more drug depots to one or more sites beneath the skin of a patient with or without repositioning the cannula. The device has a cannula capable of insertion to the site beneath the skin of the patient and one or more side port openings for delivering a drug depot. The side port openings are spaced a distance from the blunt tip, which will allow the user to implant at a set distance from a nerve. The device may also include an electronic monitor for detecting the proximity of the tip of the cannula to a nerve. In some embodiments, a method of delivering a drug depot is provided by detecting the nerve and delivering the drug depot at or near the nerve.

Device and method for directional delivery of a drug depot

A collagen material is disclosed and can include a plurality of particles. Each particle can include an elongated, thin body having one or more arcuate portions and one or more straight portions. Further, each particle can include one or more fibers extending from the body. One or more fibers of one particle can engage the one or more fibers of one or more other particles to establish a matrix of material, where a cross-linking agent may be added in the collagen material. Furthermore, an additive including a radiocontrast medium, a drug, a cellular matter, a biological factor, or a combination thereof may be added to the collagen mixture.

Injectable collagen material

The invention relates to a biocompatible settable polymer useful in retaining an implant, more evenly distributing any force loading on the implant, and/or promoting tissue growth around and onto the implant.

Method for stabilizing an intervertebral disc device

Drug depot storage and delivery devices and methods for delivering a drug depot to a site beneath the skin of a patient are provided. In various embodiments, the drug depot storage and delivery device comprises a retaining member that in an open position allows delivery of the drug depot from the drug cartridge to the target tissue site. In various embodiments, the drug depot storage and delivery device comprises a retaining member that in a closed position reduces or prevents delivery of the drug depot from the drug cartridge to the target tissue site.

Drug storage and delivery device having a retaining member

A multiple component cartridge includes a barrel defining a chamber and a longitudinal axis. A first plunger is disposed within the chamber and in sealing engagement with the barrel. The first plunger includes at least one member and is movable relative to the barrel such that the at least one member is configured for movement relative to the first plunger to facilitate passage of at least a first component through the first plunger. A second plunger is disposed within the chamber and in sealing engagement with the barrel. The second plunger includes at least one member and is movable relative to the barrel such that the at least one member of the second plunger is configured for movement relative to the second plunger to facilitate passage of at least a second component through the second plunger.

Multiple component mixing and delivery system

A collagen delivery device is disclosed and can include a barrel having a syringe chamber. Further, a syringe can be disposed within the syringe chamber. The syringe can include a collagen material therein. Additionally, the collagen delivery device can include a plunger within the barrel. The plunger can be moved to expel the collagen material from the syringe.

Collagen delivery device

The disclosure is directed to a needle system configured to enlarge an access path in a patient without further cutting into the tissue of the patient so as to reduce recovery time and trauma to the patient. Also provided are methods of using the needle system provided.

Growing community of inventors

Memphis, TN, United States of America

Thomas Andrew Simonton