The Texas A&m University System

Thomas A Ficht

Leslie Garry Adams

Allison R Ficht

Renee Tsolis

L Garry Adams

Angela M Arenas-Gamboa

Blair A Sowa

Joe W Templeton

Roger Smith, Iii

Donald S Davis

Angela M Arenas Gamboa

Albert M Wu

John D Williams

Richard P Crawford

Methods and compositions for the treatment ofinduced diseases and disorders are disclosed herein. In preferred embodiments, the invention relates to vaccines. In additional embodiments, the invention relates to formulations capable of releasing said vaccines at a controlled rate of release in vivo. In further embodiments, the invention relates to modified strains of the bacteriaand. In still further embodiments, the invention relates to compositions that do not induce clinical symptoms or splenomegaly in a subject receiving said compositions.

Controlled release vaccines and methods of treatingdiseases and disorders

Methods and compositions for the treatment ofinduced diseases and disorders are disclosed herein. In preferred embodiments, the invention relates to a vaccine compositions and methods of vaccinating comprising: acomprising one or more attenuating gene knockouts; and a pharmaceutically acceptable vaccine carrier.

vaccine for dogs

Controlled release vaccines and methods for treatingdiseases and disorders

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The present invention is an improved vaccine against Brucella abortus which permits differentiation between vaccinated and field strain infected cattle. The vaccine can be administered in two different forms: (1) cell envelopes isolated from an O polysaccharide antigen deficient, stable transposon mutant of B. abortus or (2) an O polysaccharide antigen deficient, stable transposon mutant of B. abortus.

Vaccine comprising Brucella abortus which has O polysaccharide antigen

A method for detecting Brucella infection in an animal which is reliable, rapid, and able to identify species and biovars of Brucella. The detection method includes the amplification of the omp2 gene locus of Brucella and analysis of restriction digestion fragments specific to Brucella and to individual species and groups of biovars of Brucella.

Probes and method for identifying species and biovars of brucella

Method for detecting species and biovars of Brucella

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College Station, TX, United States of America

Thomas A Ficht