Nemera La Verpilliere S.a.s.

Societe De Conseils De Recherches Et D'applications Scientifiques (s.c.r.a.s.)

Compagnie Plastic Omnium

Fresenius Kabi Deutschland Gmbh

Rexam Pharma La Verpilliere

Rexam Healthcare La Verpilliere

Nemera La Verpilliere

Ipsen Pharma

Ascil Proyectos Sl

Thierry Rimlinger

Gaëtan Painchaud

Thierry Decock

Xavier Julia

Guillaume Grevin

Roland Cherif-Cheikh

Pascal Dugand

Christophe Aubert

Philippe Dodier

Fabrice Bonacci

Michel Pouget

Serge Barneaud

Torsten Brandenburger

Sylvain Lanzi

Christian Ebert

Alexander Degen

Rodrigue Chatton

Kevin Reitz

Fabien Vaudant

Florence Roger

Matthew Egerton Young

Julien Brand

Grant Timothy Lewis Smetham

Julian Richard Dixon

Thierry Peysson

Guillaume Belle

Roland Chérif-cheikh

A prefilled syringe and a method of filling a syringe with a pegfilgrastim solution to provide a target extracted volume of pegfilgrastim solution from the syringe are described. A method includes selecting the target extracted volume of pegfilgrastim solution, determining an estimated drug transfer loss, determining an estimated syringe dead volume, filling the syringe with a volume of pegfilgrastim solution comprising at least the target extracted volume plus the estimated drug transfer loss plus the estimated syringe dead volume.

Prefilled syringe with pegfilgrastim having optimized dose and methods related thereto

A tip for dispensing liquid for mounting on a container. A valve includes at least two elements that are mobile in relation to one another, each mobile element including a bearing zone against the other mobile element. One of the mobile elements bears anti-microbial material on or in the immediate proximity of a part of its bearing zone forming a blocking barrier and all surfaces of the dispensing tip in contact with the inside are free of anti-microbial material.

Nozzle and container for dispensing a liquid

The syringe comprises a body containing the liquid and having fitted thereto an endpiece for fastening a needle carrier. The safety device comprises a protective sheath and a syringe support that is received inside the sheath. The sheath and the support are axially movable relative to each other between two positions, namely an uncovered position of the needle, and a retracted position of said needle. The support includes anti-rotation means for constraining it in rotation about its axis and comprising at least one pawl urged resiliently into a position in which the pawl is designed to co-operate with complementary anti-rotation means of the fastener endpiece. The sheath and the support include complementary anti-rotation means for constraining them in rotation relative to each other about their axes and activated at least when the sheath and the support are in their uncovered position of the needle.

Safety device for a liquid injection syringe, and a syringe assembly including the device

A syringe assembly including a syringe and a safety device, the syringe including a barrel of tubular shape, the safety device including a member of tubular shape referred to as a syringe support in which the barrel is arranged such that the syringe support and the barrel are secured on the same axis. The syringe barrel has a flange at a proximal end that is prevented from moving in translation between a peripheral bearing seat and an abutment of the support. Interposed between the seat and the flange, the assembly includes at least one compression pad between the seat and the flange and made of a material presenting a coefficient of friction relative to at least one of the materials of the flange and of the seat that is greater than the coefficient of friction of the materials of the flange and of the seat relative to each other.

Syringe and safety device assembly

A device for dispensing liquid including a liquid reservoir which can be deformed so as to dispense liquid by pressing on the reservoir, a liquid-dispensing end piece fitted on the reservoir, a channel for the passage of liquid, a channel for the passage of air from the outside to the inside of the reservoir, the channel for the passage of air being closed off by a member made of an air-permeable polymeric material, this material being non-porous, the member being called the air-permeable member.

Device for dispensing liquid in the form of drops

The invention concerns a device for injecting a solid medicine () comprising a body () inside which moves along a general forward moving axis (X-X) a bevelled () needle () wherein is introduced the medicine (), said injection device () further comprising retaining means for preventing the medicine from falling () prior to being injected. The invention is characterized in that the medicine () is retained through an elastic deformation imparted to the needle () by the retaining means or by an elastic deformation of the retaining means themselves, or still by the combined flexibility of those two means.

Device for injecting a pharmaceutical active principle

The invention relates to a safety device () for a syringe (), the device comprising a protective sheath () in which the syringe () can slide, said sheath () presenting an opening () at a distal portion (), which opening is suitable for allowing the syringe () to project beyond the sheath (). According to the invention, the sheath () presents radial resilience at its distal portion () suitable for enabling the sheath () to receive a cylinder () of diameter greater than that of said opening ().

Safety device for a syringe

The invention relates to a device which is used to inject an implant () into tissues (). The inventive device is characterized in that it comprises: a main hollow body (') having a hollow needle (&#x2032;) fixed thereto, into which the implant () is introduced; a secondary body (&#x2032;) which is disposed coaxially inside the main body (&#x2032;) and which surrounds the needle (&#x2032;); and a plunger rod (&#x2032;) which can slide coaxially inside the hollow needle (&#x2032;). The injection device (&#x2032;) is arranged such that: (i) when it is pressed against the tissues (), the main body (&#x2032;) slides along the length of the secondary body (&#x2032;) from a proximal position to a distal position such that the needle (&#x2032;) can penetrate the tissues (), whereby the movement of the main body (&#x2032;) is accompanied by the concomitant movement of the plunger rod (&#x2032;); and (ii) the plunger rod (&#x2032;) remains fixed and maintains the implant () at the required depth in the tissues () until the needle (&#x2032;) is removed therefrom when the main body (&#x2032;) is returned from the distal position to the proximal position.

Device for the injection of a solid or semi-solid implant

The invention concerns a device for back injecting an implant () into the skin () of a subject, said device () include a hollow main body (), to which a hollow needle () is fixed into which the implant () is introduced, a secondary body () coaxially arranged inside the main body () and surrounding the needle () and a piston rod () able to slide coaxially inside said hollow needle () and whose position relative to said needle () remains unchanged when the back injection device () is pressed against the subject's skin () to allow the needle () to penetrate said subject's skin and when the secondary body () retracts inside the main body (), the piston rod () penetrating the interior of the hollow needle () to hold the implant () at the required depth in the subject's skin () during withdrawal of the hollow needle () from the subject's skin (), during which the secondary body () exits the main body (), characterized in that it includes means for the elastic return of the secondary body () from the main body ().

Implant back-injecting device

The assembly comprises a body forming a reservoir for the liquid, the body being provided with a liquid-injection needle, a plunger mounted to be axially movable in the body between a ready position and an end-of-injection position, and a sheath in which the body is mounted to be axially movable between an active position in which the needle projects from a distal end of the sheath, and a protecting position in which the needle is retracted inside the sheath. The assembly also comprises means for axially securing the plunger and the sheath in a relative position of said plunger and said sheath serving firstly to position the body in its protecting position relative to the sheath and secondly to position the plunger in its end-of-injection position relative to the body.

Liquid-injection syringe assembly, and a sheath for the assembly

The security assembly is designed to be fitted to a syringe comprising a body provided with one end for connection to an injection needle and one end for inserting a piston. The security assembly comprises a member for fitting to the body of the syringe so as to be constrained axially relative to the body, and a security cap for covering the injection end of the body, the cap being provided with a proximal portion for connection to the fitted member and a distal portion for releasing the injection end and connected to the connection portion by frangible means. The fitted member forms a member that is designed to retain the piston inside the body.

Security assembly for fitting to a syringe, and a syringe assembly

The present invention relates to a safety device () for a prefilled syringe (), the syringe comprising a body (), a needle carrier (), a piston () movable inside the body, and a piston rod () suitable for pushing the piston inside the body towards the needle carrier. The device comprises a protective sheath () in which the syringe body can slide between an injection position and a safe position in which the needle is withdrawn inside the sheath, said device () comprising a resilient element () suitable for acting on the syringe to bring in into its safe position after injection, said resilient element presenting two axial ends and comprising at least two elastically-deformable arms extending between said two axial ends, one of the ends () being arranged so as to be capable of sliding freely relative to the piston rod () prior to injection, and/or one of the ends being arranged in such a manner as to be capable of being fixed to the protective sheath () in a position of adjustable height.

Security device for a syringe

Growing community of inventors

L'Isle d'Abeau, France

Thierry Rimlinger