Theraclion

Arrow International Limited

Theraclion Sa

Centre National De La Recherche Scientifique

Institut National Des Sciences Appliquees De Lyon

Arrow International Investment Corp.

Theraclion Sas

Arrow International Investments Corp.

Thierry Pechoux

Gerard Hascoet

Francois Lacoste

Anthony Grisey

Jérémie Anquez

Sylvain Yon

François Lacoste

Roberta Brocardo

Didier Vray

The invention relates to a device for treatment of a tissue of a living being, including a transducer for emitting a beam of ultrasound waves mounted on a movable treatment head, an ultrasonic imaging device optionally an inflatable balloon surrounding the treatment head and containing a coupling fluid, and a control unit for controlling the movement of the treatment head and the operation of the transducer and the imaging device wherein the treatment head is adjustable to at least two of a treatment position, a monitoring position and a travel position in order to avoid displacement of tissues during displacement of the treatment head an increase imaging quality.

Device for treatment of a tissue and method of preparation of an image of an image-guided device for treatment of a tissue

A device for treatment of a tissue () of a living being, including a transducer () for emitting a beam of ultrasound waves mounted on a movable treatment head (), an ultrasonic imaging device (), optionally an inflatable balloon () surrounding the treatment head () and containing a coupling fluid, and a control unit for controlling movement of the treatment head () and operation of the transducer () and the imaging device (). In order to avoid displacement of tissues () during displacement of the treatment head () and increase imaging quality, the treatment head () is adjustable to at least two of a treatment position (T), a monitoring position (M) and a travel position (S).

A coupling liquid for ultrasound devices, preferably high intensity focused ultrasound (HIFU). The coupling liquid comprises a liquid aqueous solution of at least one hydrophilic polymer having an average molecular mass of between 30,000 and 70,000 and at least one alcohol with a carbon chain of 1 to 7 carbon atoms. Also disclosed is a container () for an ultrasound coupling liquid having a thin wall.

Ultrasound coupling liquid and container

This invention relates to a coupling liquid for ultrasound devices, preferably high intensity focused ultrasound (HIFU). The coupling liquid comprises a liquid aqueous solution of at least one hydrophilic polymer having an average molecular mass of between 30,000 and 70,000 and at least one alcohol with a carbon chain of 1 to 7 carbon atoms. Also disclosed is a container () for an ultrasound coupling liquid having a thin wall.

This invention concerns a cover member, especially for a HIFU head, comprising a peripheral outer wall, an open first side configured to partially cover an ultrasound head and a closed second side comprising a flexible membrane adapted for contact with a patient's skin, characterized in that the cover member is removeably attachable to the tip of said ultrasound probe.

Cover, a treatment device and a method of use of such a device

A device for therapeutic treatment includes an acoustic transducer designed to emit power waves to treat a target, and an imaging probe designed to emit waves for providing an image representation of the target and its environment before, during and after the emission of the power waves issuing from the transducer. The probe and the transducer are integrally connected to one another other. The device also includes a display for displaying images taken by the probe, namely images at rest, taken before and/or after emission of the power waves, and interference images, taken during the emission of the power waves. The device additionally comprises a detector for detecting a change of structure of the interference images that is indicative of the efficacy of the power waves.

Device for therapeutic treatment

A method of tracing the likely contour of an anatomical element in a sectional image of an anatomical site, the image being composed of pixels having different intensities, the method including the steps of: a) forming columns of pixels passing through the anatomical element; b) assigning each pixel a pixel score representing the probability of the pixel being situated on the contour of the anatomical element; c) constituting a matrix of pixel scores from a plurality of columns of pixels and defining numerous continuous paths of pixels, each passing through a single pixel of each column; d) assigning each continuous path a path score that is a function of the scores of the pixels constituting the continuous path; e) selecting from a set of continuous paths the path that has the best path score, that path representing the likely contour of the anatomical element.

Method of tracing the likely contour of an anatomical element on an image of a cross section

A therapeutic treatment head for treating living tissue (T), the head comprising a casing (), an ultrasound therapeutic transducer () mounted on the casing, and a diaphragm () mounted on the casing (), the diaphragm () being designed to come into contact with an application surface (S) of the tissue (T), such as skin; the diaphragm (), the transducer (), and the casing () together defining a chamber () that is filled with an acoustic coupling liquid (L) that flows through the chamber between an inlet () and an outlet (); the transducer () being placed in such a manner as to emit ultrasound through a propagation zone (Z) of the chamber towards the diaphragm (); the head being characterized in that a first temperature sensor () is placed close to the inlet () and a second temperature sensor () is placed close to the outlet (), the sensors () delivering signals that are representative of temperatures.

Therapeutic treatment appliance

The present invention relates to a method and associated apparatus for improving the accuracy with which the speed of a fluid, such as a liquid, in particular blood flowing in a duct, such as a blood vessel, in particular the aorta, is measured by means of a signal emitted by a Doppler transducer (). In characteristic manner, according to the method, the Doppler transducer is associated with a programmable memory () which contains at least one correction data item for correcting the Doppler signal transmitted by the transducer () to a transducer control and computer unit (). Said computer unit () incorporates said signal correction data item in its computation (at) of each speed measurement on the basis of each signal emitted by the Doppler transducer, and it computes the speed value while taking account of said correction data item so as to provide a corrected measurement of the speed of said fluid, thereby improving its accuracy.

Method and apparatus for improving the accuracy with which the speed of a fluid is measured

The invention relates to a device for protecting a cover. According to the invention, said cover is flexible and tubular in shape being closed at one end and open at its other end, and said cover is disposed at least in part inside a hollow tubular protective element referred to as a protective tube, which element is open at both ends. The device of the invention is particularly suited for use in the medical field, in particular for covering, preferably in sterile manner, a tool that is to be inserted in an animal or a human being, in particular in a natural passage such as the esophagus, the urethra, the rectum, or a blood vessel.

Device for protecting a cover, the use of a device for protecting a cover, a method of fitting a cover on a probe, and a method of making a device for protecting a cover

The present invention relates to a method and associated apparatus for improving the accuracy with which the speed of a fluid, such as a liquid, in particular blood flowing in a duct, such as a blood vessel, in particular the aorta, is measured by means of a signal emitted by a Doppler transducer ( ). In characteristic manner, according to the method, the Doppler transducer is associated with a programmable memory ( ) which contains at least one correction data item for correcting the Doppler signal transmitted by the transducer ( ) to a transducer control and computer unit ( ). Said computer unit ( ) incorporates said signal correction data item in its computation (at ) of each speed measurement on the basis of each signal emitted by the Doppler transducer, and it computes the speed value while taking account of said correction data item so as to provide a corrected measurement of the speed of said fluid, thereby improving its accuracy.

Device for protecting a cover on a probe

The present invention relates to a method and associated apparatus for improving the accuracy with which the speed of a fluid, such as a liquid, in particular blood flowing in a duct, such as a blood vessel, in particular the aorta, is measured by means of a signal emitted by a Doppler transducer (,). In characteristic manner, according to the method, the Doppler transducer is associated with a programmable memory (,) which contains at least one correction data item for correcting the Doppler signal transmitted by the transducer (,) to a transducer control and computer unit (,). Said computer unit (,) incorporates said signal correction data item in its computation (at,) of each speed measurement on the basis of each signal emitted by the Doppler transducer, and it computes the speed value while taking account of said correction data item so as to provide a corrected measurement of the speed of said fluid, thereby improving its accuracy.

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Paris, France

Thierry Pechoux