Coris Bioconcept

Coris Bioconcept Sprl

Thierry Leclipteux

Pascal Y Mertens

Laurence Denorme

Ismaelle Renuart

Pierre Bogaerts

Laetitia Avrain

Te-Din Huang

Isabelle Ote

Gerald Glupczynski

Eric Aussems

Valérie Smekens

Devices for detecting analytes or analogues thereof in a biological sample are disclosed. The device includes a solid support. The solid support has several juxtaposed zones. The sample is able to migrate from a sample receiving zone towards a detection zone. The analyte, if present, is detected in the detection zone. Both zones have material allowing a capillary flow of the sample through the zones. In between the zones, there is an intermediate zone of transport of the sample which is free from any capillary material. This allows the ample to migrate by gravitational forces on the support laid in a vertical position. Methods for detecting analytes or analogues thereof in a biological sample using the device are also disclosed.

Test device for rapid diagnostics

The present invention relates to methods and devices for detecting one or more analytes in a biological sample, preferably a clean liquid sample. This invention in particular relates to improved rapid tests such as 'dipsticks', 'lateral flow' devices and &#x201c;flow-through&#x201d; devices. The invention in particular relates to oligochromatographic devices that make use of a peptide- or hapten-coupled oligonucleotide and a reagent specifically recognizing the hapten or peptide and a conjugated probe that hybridizes specifically to a target sequence. It allows to detect specifically the presence of a polynucleotides directly or after molecular amplification steps with the use of a specific genuine internal control and a chromatographic control.

One step oligochromatographic device and method of use

Growing community of inventors

Wepion, Belgium

Thierry Leclipteux