Invectys

Invectys Sa

Centre National De La Recherche Scientifique

Thierry Huet

Pierre Langlade Demoyen

Julien Caumartin

Maria Loustau

Christelle Liard

Maria Wehbe

Simon Wain-Hobson

Elodie Pliquet

Luis Maria Mir

Jessie Thalmensi

Christophe Calvet

Anna Kostrzak

Luis M Mir

The invention provides a nucleic acid construct comprising a sequence that encodes a human telomerase reverse transcriptase (hTERT) protein which is devoid of telomerase catalytic activity and of a nucleolar localization signal. The construct is useful triggering an immune response in a subject, against cells that overexpress telomerase, preferably dysplasia cells or tumor cells.

Telomerase encoding DNA vaccine

The present invention relates to antibodies, or antigen-binding fragments thereof, directed against human leukocyte antigen-G (HLA-G) protein and raised against an immunogenic peptide derived from the &#x3b1;3 domain of HLA-G protein. The invention further relates to the immunogenic peptide, and methods for producing said anti-HLA-G specific antibodies.

Anti HLA-G specific antibodies

The present invention relates to methods for transferring a nucleic acid in vivo into skin cells wherein the nucleic acid is injected by intradermal (ID) injection and is electrically transferred into skin cells with a single pulse of a High Voltage, followed, after a defined lag time, by a single pulse of Low Voltage.

Gene electrotransfer into skin cells

Growing community of inventors

Nogent-Sur-Marne, France

Thierry Huet