Fresenius Medical Care Deutschland Gmbh

Thierry Eyrard

Philippe Laffay

Benoit Luaire

Bruno Faye

Benoît Luaire

Benoît Luarie

The invention relates to a method for manufacturing a liquid acid concentrate for hemodialysis machines, with the following steps. In a preliminary step a water source (), an acid source (), an electrolyte tank () containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source () are connected to a mixing tank (). During Step a), the quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank (). At Step b), the quantity of acid needed for manufacture the liquid acid concentrate is introduced into the mixing tank (), the solution is stirred until a homogeneous solution is obtained. Step c) is to repeat Sub-steps c1) and c2) until the electrolyte mixture contained in the electrolyte tank is completely dissolved. At Sub-step c1) part of the solution contained in the mixing tank () is transferred into the electrolyte tank () containing the electrolyte mixture, then at Sub-step c2) the solution contained in the electrolyte tank () is transferred into the mixing tank, leaving the still solid constituents in the electrolyte tank. At Step d) the quantity of sodium chloride needed to manufacture the liquid acid concentrate is introduced into the mixing tank (). Finally, at Step e), the solution is stirred and recirculated by taking it from the bottom the mixing tank () and reintroducing it at the top of the mixing tank until a homogeneous liquid acid concentrate is obtained. Steps a) to d) can be performed in any order, Step a) preceding always Step c).

Method, facility and tank for the manufacture of a liquid acid concentrate used for hemodialysis machines

A water source, an acid source, an electrolyte tank containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source are connected to a mixing tank. A quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank. A quantity of acid needed for manufacture of the liquid acid concentrate is introduced into the mixing tank, the solution is stirred until a homogeneous solution is obtained. Part of the solution contained in the mixing tank is transferred into the electrolyte tank, then the solution contained in the electrolyte tank is transferred into the mixing tank. A quantity of sodium chloride needed to manufacture the liquid acid concentrate is introduced into the mixing tank. The solution is stirred and recirculated until a homogeneous liquid acid concentrate is obtained.

The present invention relates to a novel dry acid concentrate (DAC) for a dialysis liquid and to a dialysis liquid, which is made from said concentrate, and which may be used for purifying blood. The invention further relates to a method of making the dry acid concentrate as well as the dialysis liquid. It also relates to a container () comprising said acid concentrate, and which is&#x2014;in certain embodiments&#x2014;specially adapted to a dialysis unit.

Dry acid concentrate in granulate form

A dry peritoneal dialysis (PD) concentrate system may be used in connection with a PD cycler. The dry PD concentrate system includes a concentrate container with at least two concentrate compartments, and at least one of the compartments contains a dry PD concentrate component. At least one of the concentrate compartments has a medical fluid outlet, and at least one of the concentrate compartments has a diluent inlet.

Dry peritoneal dialysis concentrate system

A container containing a concentrate for dialysis includes a pouch or cartridge containing a solid concentrate of constituents for the dialysis solution, the pouch or cartridge being closed by a connector having a filling channel extending completely through the connector, which is for filling the pouch or cartridge with the solid concentrate, means for introducing a solution-forming liquid into the pouch or cartridge and for extracting the solution obtained, these introduction and extraction means having at least one connecting portion for connecting them to a corresponding port of the dialysis machine. The filling channel is closed by a stopper which has a reservoir containing a second constituent or group of constituents for the dialysis solution, and means for producing an outlet opening in the reservoir contacting the inside of the reservoir with the side of the stopper located in the container.

Container for dialysis

A container for a solid product for dialysis has a connector () for connection to a dialysis machine, with a filling channel () that crosses it from one end to the other for filling the receptacle with solid product; a fluid line () for introducing a solution-making liquid, extending between a first connecting portion () that opens to the outside and an orifice () that opens to the inside; and a fluid line () for extracting the obtained solution, extending between a second connecting portion () that opens to the outside and an orifice () that opens to the inside. The filling channel () is open at both ends and the two fluid lines () are fluid-tight between the orifice () that opens into the receptacle and the first or second connecting portion (), respectively.

Connector for dialysis container, container equipped with such connector, manufacturing and filling method for such connectors and containers

A concentrate container for preparing a medical fluid, preferably for preparing a dialysis solution, is provided, the concentrate container including at least two concentrate compartments, wherein at least one of the concentrate compartments has a medical fluid outlet, and at least one of the concentrate compartments has a diluent inlet. Further, systems for preparing a medical fluid and a method for preparing a medical fluid are described.

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Lyons, France

Thierry Eyrard