Solvay Sa

Solvay (societe Anonyme)

Alba Therapeutics Corporation

Solvay

Peptisyntha Sa

Thierry Delplanche

Roland Callens

Olivier Jacques F J G Bodson

Patrick Perrin

Antonella Gervasini

Dirk Breugelmans

Thierry Le Mercier

Georges Blondeel

Lauriane D'Alencon

Marc Thijssen

Perrine Davoine

Aziz Mimouni

Sarah Khirani

Yves Antoinette

Beatrice Ortego

Sabrina Bedel

Olivier Jacques Bodson

Olivier Jacques FJG Bodson

Eric Coudry

A process for producing a calcium phosphate reactant, according to which: in a first step, use is made of a source of calcium and a source of phosphate ions in water, in a molar ratio that is adjusted so as to obtain a Ca/P molar ratio of between 0.5 and 1.6, and the source of calcium is reacted with the phosphate ions at a pH of between 2 and 8, in order to obtain a suspension (A) of calcium phosphate, and in a second step, added to the suspension (A) are an alkaline compound comprising hydroxide ions in order to set a pH of more than 8 and an additional source of calcium in order to obtain a suspension (B) of calcium phosphate reactant having a Ca/P molar ratio of more than 1.6. A calcium phosphate reactant obtainable by such a process.

Process for producing a calcium phosphate reactant, reactant obtained and use thereof in the purification of liquid effluents

A composite comprising a hydroxyapatite and at least one additive which is present during hydroxyapatite synthesis. The additive may be embedded or incorporated into or coated onto the hydroxyapatite. The additive preferably increases the hydroxyapatite porosity, e.g., providing a higher pore volume and/or BET surface area than a hydroxyapatite material without additive. The additive preferably comprises an activated carbon, chitosan, hopcalite, clays, zeolites, sulfur, and/or a metal such as Al, Sn, Ti, Fe, Cu, Zn, Ni, Cu, Zr, La, Ce, in the form of metal, salt, oxide, oxyhydroxide, and/or hydroxide. The hydroxyapatite may be calcium-deficient. The composite is in the form of particles having a D50 of at least 20 &#x3bc;m, a BET surface area of at least 120 m/g; and/or a total pore volume of at least 0.3 cm/g. An adsorbent material comprising a composite or a blend of composite with a hydroxyapatite without additive, and its use for removal of contaminants such as Hg, Se, As, and/or B from an effluent.

Hydroxyapatite composite for use in removal of contaminants from effluents and methods of making

A porous material comprises at least 60 wt % of a calcium-deficient hydroxyapatite having a Ca/P molar ratio of less than 1.67, having a specific BET surface area of at least 110 m/g and a pore volume of at least 0.41 cm/g, both measured after heat treatment at 120&#xb0; C. A catalyst composition for catalytic reduction of NOcompounds, comprising an active catalyst component: Cu and/or CuO deposited on the porous material as support. A deNOx process according to which an ammonia source is injected into a combustion waste gas stream containing NOx; and to which the catalyst composition is brought into contact with the waste gas stream at a temperature of at least 100&#xb0; C. and preferably at most 600&#xb0; C. to carry out, in the presence of O, a reduction by NHof at least a portion of the NOx.

Copper supported catalyst comprising a Ca-deficient hydroxyapatite for waste gas NOx removal

Process for treating a combustion waste gas stream containing NOx and contaminants such as heavy metals and/or acid gases, e.g., halogens, SOx, comprising: injecting an alkali sorbent, into the waste gas stream; removing some contaminants with the alkali sorbent from the waste gas stream; injecting an ammonia source into the gas stream; injecting a deNOx catalyst into the gas stream at a temperature of 100&#xb0; C. to preferably not more than 600&#xb0; C. to reduce with NH3, in the presence of O, some NOx to Nand water in the gas stream, wherein the deNOx catalyst comprises copper and/or copper oxide deposited on a porous support comprising at least 60 wt % of a calcium-deficient hydroxyapatite having a Ca/P of less than 1.67. A blend comprising the alkali sorbent and the deNOx catalyst may be formed to inject them together into the waste gas stream. The ammonia source and the deNOx catalyst are preferably injected simultaneously. Alternatively, the ammonia source may be included in the alkali sorbent and/or the deNOx catalyst.

Multi-pollutant gas purification process with alkali sorbent and deNOx supported catalyst comprising Ca-deficient hydroxyapatite

The invention provides crystalline forms of the peptide Gly-Gly-Val-Leu-Val-Gln-Pro-Gly (SEQ ID NO 1), and salts of the peptide, which may further have associated water molecules. These salts and hydrated salts of the peptide and compositions comprising these materials have advantageous pharmaceutical properties.

Larazotide acetate compositions

Process for the manufacture of a peptide or peptide analog, which comprises (a) producing a persilylated peptide or persilylated peptide analogue by silylating a corresponding peptide by reaction with a silylating agent other than trimethylsilylcyanide, and (b) reacting a compound of formula (I) X-A-COOH wherein X is an amino protecting group, A is an amino acid, peptide or peptide analogue residue, and &#x2014;COOH designates an optionally activated carboxylic group, with a persilylated peptide or a persilylated peptide analogue containing from 4 to 15 amino acids.

Process for the manufacture of persilylated peptides

Process for the separation of enantiomers comprising at least one free functional group, in which process a reagent based on an enantiopure amino acid is reacted in basic medium with a mixture comprising enantiomers.

Process for the separation of enantiomers and enantiopure reagent

Process for the separation of enantiomers comprising at least one free functional group, in which process a reagent based on an enantiopure amino acid is reacted in basic medium with a mixture comprising enantiometers.

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Mont-St-Guibert, Belgium

Thierry Delplanche