Zymogenetics, Inc.

Immunex Corporation

Theresa M Farrah

Si Lok

Theodore E Whitmore

Robyn L Adams

Anna C Jelmberg

Richard Jeffrey Armitage

Melanie K Spriggs

Mark R Alderson

Jeffrey I Cohen

Michael R Comeau

Choon J Kho

Lindsey M Hutt-Fletcher

Paul O Sheppard

Darrell C Conklin

Mark F Maurer

Angelika Grossmann

Theodore E Whitemore

Novel receptor polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides comprise an extracellular domain of a cell-surface receptor that is expressed in kidneys, pancreas, prostate, adrenal cortex and nervous tissue. The polypeptides may be used within methods for detecting ligands that promote the proliferation and/or differentiation of these organs.

Class II cytokine receptor-7

The present invention relates to polynucleotide and polypeptide molecules for ZTMPO-1, a novel soluble protein with homology to emerin and the thymopoietins. The polypeptides, and polynucleotides encoding them are useful for modulating cellular proliferation and differentiation and may be used for diagnostic purposes. The present invention also includes antibodies to the ZTMPO-1 polypeptides.

Soluble protein ZTMPO-1

Novel class II cytokine receptor polypeptides, polynucleotides encoding the polypeptides, an related compositions and methods are disclosed. Th polypeptides comprise an extracellular domain of a cell-surface receptor that is expressed in pancreas, small intestine, colon and thymus. The polypeptides may be used within methods for detecting ligands that promote the proliferation and/or differentiation of these organs.

Class two cytokine receptor-11

Class II cytokine receptor

Isolated viral proteins, and pharmaceutical compositions made therefrom, are disclosed which are capable of binding to a .beta. chain of a Class II Major Histocompatibility Complex antigen, thereby functioning to inhibit an antigen-specific response. The viral proteins also have superantigen-like activity, and inhibit EBV infection.

Isolated Epstein-Barr virus BZLF2 proteins that bind MHC class II

Isolated epstein-barr virus BZLF2 proteins that bind MHC class II beta

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Seattle, WA, United States of America

Theresa M Farrah