Medwaves, Inc.

Arthrocare Corporation

Afx Inc.

Other

Maquet Cardiovascular LLC

Fox Hollow Technologies, Inc.

Theodore C Ormsby

George L Leung

Jean Woloszko

Dany Berube

Robert E Woodard

Ming-Fan Law

Gwo Jenn Shen

Craig Tsuji

Robert G Matheny

Terry S Davison

Lyndall Erb

Christopher Lee Willink

Peter Chu

Russell Chung

Ming Fan Law

Mir A Imran

David C Hovda

Maria B Ellsberry

Jeffrey S Frisbie

Paul O Davison

Robert H Dahla

Kevin H Van Bladel

Gregory Kent Feld

Brian E Martini

Osamu Katoh

Steve Masterson

Shen Gwo Jenn

John J Quackenbush

Scott A McGill

Carole M Sykes

George Leung

An ablation system which transmits radio frequency (RF) energy for the ablation of biological tissues has a transmission line and an RF antenna disposed at the distal portion of the transmission line. An RF signal generator supplies RF energy to the proximal end of the cable for transmission to the antenna, and an electrically tunable transformer is connected between the signal generator and the antenna. The transformer is tuned based on detection of the reflected power level from the antenna so as to reduce or minimize reflected power, thereby increasing RF energy coupling between the antenna and tissue.

Electrically tunable tissue ablation system and method

An RF ablation system has a hollow conductive coaxial cable comprising inner and outer coaxial tubular conductors, and an ablating member mounted at the distal end portion of the cable for delivery of radio frequency energy including microwaves to the target body tissue. The inner conductor has a central lumen and extends at least up to the ablating member. At least one electromagnetic tracking sensor coil with a magnetic core is located in the central lumen at the distal end portion of the cable, close to the distal tip of the cable, and connected to a signal processing unit. An electromagnetic field generator positioned in the vicinity of a patient undergoing treatment generates an electromagnetic field which induces a voltage in the sensor coil. The signal processing unit uses the induced voltage to calculate the position and orientation of the distal end portion or tip of the catheter in a patient's body.

Radio frequency ablation system with tracking sensor

An ablation device which transmits radio frequency (RF) energy for the ablation of biological tissues has elongate inner and outer coaxial conductors extending from a proximal portion to a distal portion. An RF antenna is disposed at the distal portion of the device and transmits RF energy for ablation of a tissue region to be treated. Reflection of energy from the tissue or the ablation point is reduced by providing multiple layers of dielectric media about the antenna, or by providing a gradual transition point from the conductors to the antenna tip, by means of a longitudinally stepped dielectric layer transformer.

Radio frequency based ablation system and method with dielectric transformer

A coaxial cable apparatus which transmits radio frequency (RF) energy for the ablation of biological tissues has inner and outer coaxial conductors extending substantially the entire length of the cable from a proximal end portion to a distal end portion. An RF antenna is disposed at the distal end portion of the cable and transmits RF energy for ablation of a tissue region to be treated. An angioplasty balloon is disposed over the RF antenna and communicates with a fluid supply and extraction passageway extending through the cable to allow the balloon to be inflated for an angioplasty procedure including tissue ablation, and to be deflated after the procedure is complete.

Angioplasty and tissue ablation apparatus and method

A hollow coaxial cable adapted for conduction of radio frequency (RF) energy, particularly microwave energy, has a proximal end and a distal end and comprises coaxial inner and outer conductors extending substantially the entire length of the cable from the proximal end to a distal end portion of the cable with a dielectric medium disposed between the inner and outer conductors. The inner conductor comprises an elongated electrically conductive tubular member having a hollow, axially extending lumen, and the outer conductor comprises an elongated electrically conductive tubular member disposed in a substantially coaxial relationship over at least a portion of the inner conductor. An ablating member which delivers radio frequency energy, particularly microwave energy, to body tissue is disposed at a distal end portion of the cable.

Hollow conductive coaxial cable for radio frequency based tissue ablation system

A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.

Radio frequency-based catheter system with improved deflection and steering mechanisms

A coaxial cable apparatus which transmits radio frequency (RF) energy for the ablation of biological tissues has inner and outer coaxial conductors extending from a proximal portion to a distal portion. An RF antenna is disposed at the distal portion of the cable and transmits RF energy for ablation of a tissue region to be treated. At least one ultrasonic transducer is also disposed at the distal portion of the cable to direct ultrasonic frequency energy to a tissue region. The ultrasonic transducer detects reflected ultrasonic signals from the tissue region and provides a signal output which varies dependent on the density of tissue over the monitored tissue region. The reflected ultrasonic signal can be monitored before, during, and after ablation treatment.

Tissue ablation apparatus and method using ultrasonic imaging

Radio-frequency-based catheter system with improved deflection and steering mechanisms

The present invention provides systems, apparatus and methods for selectively applying electrical energy to body tissue in order to ablate, contract, coagulate, or otherwise modify a target tissue or organ. The closed configuration is adapted for clamping and coagulating a target tissue while the apparatus is operating in the sub-ablation mode, while the open configuration is adapted for ablating the target tissue via molecular dissociation of tissue components. A method of the present invention comprises clamping a target tissue or organ with an electrosurgical probe. A first high frequency voltage is applied between the active electrode and the return electrode to effect coagulation of the clamped tissue. Thereafter, a second high frequency voltage is applied to effect localized molecular dissociation of the coagulated tissue.

Bipolar electrosurgical clamp for removing and modifying tissue

A radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency ('RF') generator for selectively generating a high frequency RF energy signal in a deployable catheter having an RF transmission line, an RF antenna mounted on the distal portion of the catheter, and a temperature sensor also mounted on a distal portion of the catheter for detecting temperature adjacent an ablation site. A control system adjusts the RF energy signal so that the detected temperature is at or close to a selected temperature setting or within a selected temperature range.

Radio-frequency based catheter system and method for ablating biological tissues

Apparatus and methods for treating an inter-vertebral disc by ablation, coagulation, shrinking, stiffening, or other treatment of disc tissue. A method of the invention includes positioning at least one active electrode within the inter-vertebral disc, and applying at least a first high frequency voltage between the active electrode(s) and one or more return electrode(s), wherein the volume of the nucleus pulposus is decreased, pressure exerted by the nucleus pulposus on the annulus fibrosus is reduced, and discogenic pain of a patient is alleviated. An apparatus of the invention includes an electrosurgical probe, an introducer needle adapted for passing the distal end of the probe therethrough, and a positioning unit for monitoring a position of the probe in relation to the introducer needle.

Apparatus and methods for treating cervical inter-vertebral discs

A securing apparatus for selectively securing an ablating element of an ablation instrument proximate to a targeted region of a biological tissue. The securing apparatus includes a support base affixed to the ablation instrument relative the ablating element, and having a support face adapted to seat against the biological tissue proximate to the ablation element. The support base further defines a passage having one end communicably coupled to a vacuum source and an opposite end terminating at an orifice at the support face. The support face together with the biological tissue forms a hermetic seal thereagainst during operation of the vacuum source to secure the ablation instrument thereagainst. Essentially, the hermetic seal and the vacuum source cooperate to form a vacuum force sufficient to retain the ablation device against the biological tissue.

Vacuum-assisted securing apparatus for a microwave ablation instrument

A directional ablation instrument for ablation of a targeted tissue. The instrument includes a transmission line having a proximal portion suitable for connection to an electromagnetic energy source, and an elongated antenna device having a longitudinal axis and an end coupled to the transmission line. The antenna is adapted to generate an electric field sufficiently strong to cause tissue ablation of the targeted tissue. An elongated support assembly includes a central axis, and an ablation surface extending longitudinally along an exterior surface portion of the support assembly. The support assembly is configured to receive the antenna device in the ablation surface such that the longitudinal axis of the antenna device is off-set from the support assembly central axis. Further, the antenna device is oriented toward the surface portion for positioning of the antenna device substantially adjacent to or in contact with the targeted tissue during operable use.

Directional microwave ablation instrument with off-set energy delivery portion

Apparatus and methods for advancing and retracting a medical instrument within an introducer device, wherein the instrument includes a distal tip, a distal linear portion, a first distal curve, a substantially linear inter-curve portion, and a second proximal curve. The length of the distal linear portion and the angle of the first curve determine the position of the distal tip within a lumen of the introducer device, such that the distal tip occupies a substantially central transverse location within the lumen and the distal tip avoids contact with the introducer device. The length of the inter-curve portion and the angle of the second curve determine deflection of the distal tip from a longitudinal axis of the shaft when the second curve is extended distally beyond a distal end of the introducer device. Also, methods and apparatus for treating an intervertebral disc by ablation of disc tissue. A method of the invention includes positioning at least one active electrode within the intervertebral disc, and applying at least a first high frequency voltage between the active electrode(s) and one or more return electrode(s), wherein the volume of the nucleus pulposus is decreased, pressure exerted by the nucleus pulposus on the annulus fibrosus is reduced, and discogenic pain of a patient is alleviated. In other embodiments, a curved or steerable probe is guided to a specific target site within a disc to be treated, and the disc tissue at the target site is ablated by application of at least a first high frequency voltage between the active electrode(s) and one or more return electrode(s). A method of making an electrosurgical probe is also disclosed.

Growing community of inventors

Escondido, CA, United States of America

Theodore C Ormsby