Wisconsin Alumni Research Foundation

University of Chicago

University of Leiden

Theo Odijk

David Charles Schwartz

Juan Jose De Pablo

Kyubong Jo

Konstantinos Dimitrios Potamousis

Kristy Leigh Kounovsky-Shafer

Juan Pablo Hernandez-Ortiz

Devices, systems, and methods for en masse patterning of nucleic acid molecule structures are disclosed. The devices can include microchannels and nanoslits. The microchannels and nanoslits can be connected by parking chambers. The systems and methods can utilize the geometry of the devices in coordination with a voltage application routine to park nucleic acid molecules in the parking chambers and subsequently inject the nucleic acid molecules into the nanoslits. The methods can be utilized to present nucleic acid molecules in a fashion suitable for genomic analysis. The methods can also be utilized to provide size selection of the nucleic acid molecules.

System and method for en masse patterning of molecule structures

Growing community of inventors

Leiden, Netherlands

Theo Odijk