Edwards Lifesciences Corporation

Warsaw Orthopedic, Inc.

Kp Medcure, Inc.

Vascular Medcure, Inc.

Endologix, Inc.

Other

Sdgi Holdings, Inc.

Vertelink Corporation

Baxter International Inc.

Onset Medical Corporation

Cerebrova Kp Medical, Inc.

Baxter Healthcare Sa

Biosense Webster, Inc.

Thanh Van Nguyen

Jay Alan Lenker

Samuel M Shaolian

To Van Pham

Duy Nguyen

George P Teitelbaum

Tung Hoang Ngo

Gilbert Madrid

Kim D Nguyen

Asher L Metchik

Trinh Van Pham

Michael R Henson

Rajan Hansji

Arvin T Chang

Darshin S Patel

Michael R Bialas

Michael J Popp

George Bakis

John Joseph Desrosiers

Jeff Lindstrom

Jun Liu

George Washington

Ly Th Phan

Raz Biran

Frank Nguyen

Vincent Divino

George F Kick

Tarannum Ishaq Gutierrez

Kees Ruzius

Timothy B Meluch

Lalith K Silva

Richard H Estes

Hunt Dabney

Chung-Yuan Chiang

Hamid Jaanine

Michael C Sherman

Lehmann K Li

James Huntington Dabney

Edward J Nance

Joseph Bishop

Anand R Rao

Amanda Kristine Anderson White

John M Radovich

Martin E Ketterer

Amanda K Anderson

George Nehmetallah

Tarannum Nagpurwala

Wenli Han

Jonnie Lee

Delores Jordan

Dibyendu De

Vy Bui

Onnick Tchulluian

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.

Axial lengthening thrombus capture system

A prosthetic implant delivery assembly includes a prosthetic implant and a catheter. The prosthetic implant includes a plurality of apices with apertures. Each apex of the plurality of apices is circumferentially-spaced apart relative to an adjacent apex. The catheter includes a plurality of arms and a plurality of locking elements. Each of the arms includes an opening configured to receive a respective apex of the prosthetic implant. Each of the locking elements is configured to extend through the aperture of a respective apex of the prosthetic implant. A length of at least one of the locking elements is different than a length of another locking element such that when the prosthetic implant is coupled to the catheter by the locking elements, a longitudinal axis of the prosthetic implant can be held at a tilted position relative to a longitudinal axis of the catheter.

Methods for controlled heart valve delivery

Various embodiments of devices and methods of use are provided. The device can include a catheter shaft having a proximal end and a distal end. The device can include an extractor. The extractor can include engagement panels located at a first longitudinal location and engagement panels located at a second longitudinal location. The extractor can include a spacer between engagement panels located at the first longitudinal location and engagement panels located at the second longitudinal location. The device can include a sheath, wherein the extractor comprises a collapsed state within the sheath for delivery and an expanded state within a blood vessel. In the expanded state, the engagement panels are configured to engage material between engagement panels located at a first longitudinal location and engagement panels located at a second longitudinal location.

Neurovascular clot retrieving system

A method for retrieving a previously inserted prosthetic valve is disclosed. In one example, a loader assembly is inserted through a hub of a delivery sheath device. The delivery sheath device includes an expandable sheath that extends into a blood vessel of a patient. The loader assembly is advanced in a distal direction until a distal section of the loader assembly extends into the expandable sheath which is attached to a distal end of the hub. The distal section has a larger inner diameter than a middle tube section of the loader assembly. A delivery catheter is retracted to move a prosthetic valve attached thereto in a proximal direction until the prosthetic valve is received within the distal section. The loader assembly and the delivery catheter are removed from a proximal end of the hub while the prosthetic valve is retained within the distal section.

Loader and retriever for transcatheter heart valve, and methods of crimping transcatheter heart valve

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism, deep vein thrombosis, cerebrovascular embolism, and other vascular occlusions. The capture system can include a tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an opening and a capture guide. The capture system can include one or more tensioners coupled to the capture guide. The tubular body has a first configuration in which the first end and the capture guide are expanded while the second end and a majority of the tubular body remains compressed. The tubular body is transformable to a second configuration by application of tension by the tensioners. The catheter can remove a large volume of clot.

Axial lengthening thrombus capture system, tensioning system and expandable funnel catheter

In some examples, a capture assembly configured to remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system, includes a body configured to receive the material of interest. The body can be configured to axially lengthen and shorten.

Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.

Prosthetic heart valve delivery apparatus

Embodiments of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such embodiments can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some embodiments can include a sheath with inner and outer layers, where a folded portion of the inner layer extends through a slit in the outer layer and a portion of the outer layer overlaps the folded portion of the inner layer. Some embodiments include an elastic outer cover positioned outside the outer layer. Embodiments of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel, thus offering advantages over prior art introducer sheaths.

Expandable sheath for introducing an endovascular delivery device into a body

A loader and method for loading a transcatheter heart valve into a delivery sheath or catheter is described that is also configured to facilitate retrieval of the heart valve back through the delivery sheath while protecting the delivery sheath from damage. Another loader provides for easier crimping and loading of a THV into a delivery sheath or catheter from a storage jar or container. A method for crimping a THV facilitates easier end user preparation of the valve for implantation and reduces the likelihood of tissue deformation in the valve during storage. These devices and methods for deploying THVs simplify the valve replacement procedure.

Growing community of inventors

Irvine, CA, United States of America

Thanh Van Nguyen