Otsuka Pharmaceutical Factory, Inc.

Otsuka Pharmaceutical Company, Limited

Mitsubishi Kagaku Latron, Inc.

Mitsubishi Chemical Medience Corporation

Tetsuya Tachikawa

Kiyonori Katsuragi

Ayako Nishimura

Fumio Shimizu

Eiji Sakashita

Suguru Akamatsu

Nobuhiro Ikei

Tokio Sawai

Kenichi Imagawa

Kazuo Hino

Atsunari Noda

Kiyotoshi Sekiguchi

Kaneji Asakawa

Atunari Noda

Sadahito Shin

Hisanobu Hirano

Etsuro Hashimura

A latex reagent for analyzing adiponectin, comprising a suspension of latex particles carrying a substance which specifically binds to adiponectin, is disclosed. Further, a method for analyzing adiponectin, comprising (1) obtaining a biological liquid possibly containing adiponectin, and (2) bringing the biological liquid, while maintaining the state in which the biological liquid is obtained, into contact with a suspension of latex particles carrying a substance which specifically binds to adiponectin, and optically analyzing a degree of latex-particles-agglutination, is disclosed. According to the latex reagent and the method for analyzing adiponectin, a predilution or pretreatment of the biological liquid to be analyzed is not necessary. Further, the analysis can be performed rapidly and conveniently, and facilities therefor are not limited.

Latex reagent for adiponectin analysis and method of adiponectin analysis

The invention relates to a technology by which antibodies directed to sources of infection in body fluids can be assayed with high accuracy, expediency and specificity. More particularly, the invention provides an antibody immunoassay method in which the antigen-antibody reaction between a target antibody in a sample and an assay antigen is conducted in the presence of ancomponent and an antibody assay method which comprises using a reagent having a specific affinity for the Fc region of an antibody IgG as the antibody assay reagent. The invention further provides an antibody assay device comprising a solid-phase support having at least (a) a first region to which a sample is applied and (b) a second region where the antibody in the sample is reacted as disposed in such an arrangement that the sample is wicked from the first region to the second region and a labeling means for detection of the result of the reaction in the second region, characterized in that the (b) second region is provided with (i) a test site in which a ligand for capturing the target antibody to be assayed is immobilized and (ii) a control site in which a ligand for capturing an arbitrary antibody occurring in the sample is immobilized.

Method for assay of antibodies and antibody assay device

The invention provides an anti-EDA monoclonal antibody which recognizes an amino acid sequence portion in the EDA region of fibronectin (FN). The antibody of the invention has specific reactivity against EDA, in particular EDA-FN. By utilizing it, a simple and easy, high-sensitivity and high-precision immunoassay method for EDA-FN as well as a screening or diagnostic technique for EDA-FN-associated inflammatory and other diseases can be established.

Anti-EDA monoclonal antibody and a method for diagnosis of disease

An antibody of a human leukemia virus-related peptide obtained by collecting an antibody produced in a mammal body by administering to the mammal an antigen prepared by reacting a human leukemia virus-related peptide represented by formula (1):

Human leukemia virus-related peptides, a process for production thereof,

Growing community of inventors

Tokushima, Japan

Tetsuya Tachikawa