Yamanouchi Pharmaceutical Company Ltd.

Tetsuya Shiozaki, Deceased

Masuo Murakami

Isao Yanagisawa

Kenichi Tomioka

Toshinari Tamura

Hidenori Iwamoto

Yoshio Ishii

Noriyoshi Inukai

There are disclosed 20-alkoxy-16-alkyl-prostadienoic acid derivatives of the formula: ##STR1## wherein A represents ##STR2## R and R.sup.5, which may be the same or different, each represents a hydrogen atom or a lower alkyl group; and R.sup.1 and R.sup.4, which may be the same or different, each represents a lower alkyl group, and the pharmaceutically acceptable non-toxic salts thereof. These compounds have excellent pharmacological effects as prostaglandin E.sub.2 and prostaglandin F.sub.2.alpha..

20-Alkoxy-16-alkyl-prostadienoic acid derivatives

A 20-alkoxy-16-alkyl-prostadienoic acid derivative shown by the formula ##STR1## wherein A represents ##STR2## R and R.sup.5, which may be the same or different, each represents a hydrogen atom or a lower alkyl group; and R.sup.1 and R.sup.4, which may be the same or different, each represents a lower alkyl group, And the pharmacologically acceptable nontoxic salts thereof. The compounds have excellent effects as prostaglandin E.sub.2 and prostaglandin F.sub.2.alpha..

20-Alkoxy-16-alkyl prostadienoic acid derivatives

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LATE OF Misato, undefined

Tetsuya Shiozaki, Deceased