Screen Holdings Co., Ltd.

Tottori University

National University Corporation Tottori University

Tetsuya Ohbayashi

Masayoshi Kobayashi

Yasushi Kuromi

Takuya Aida

A technique capable of providing a user with information obtained by OCT imaging in a useful way, particularly for assisting in assessment of an embryo effectively. The image processing method includes acquiring original signal data indicating an intensity distribution of signal light from each position in three-dimensional space including a cultured embryo obtained by optical coherence tomography imaging, generating spherical coordinate data based on the original signal data, the spherical coordinate data indicating a relationship between each position in the three-dimensional space represented using spherical coordinates having an origin set inside the embryo and the intensity of the signal light from the position, and outputting the intensity distribution of the signal light as a two-dimensional map based on the spherical coordinate data using two deflection angles of the spherical coordinates as coordinate axes.

Image processing method for a computer to assist a user in assessment of a cultured embryo

A data processing method that is suitable for obtaining quantitative information from data obtained by OCT imaging. The image processing method includes acquiring original image data corresponding to a three-dimensional image of a cultured embryo obtained by optical coherence tomography imaging of the embryo and executing a region segmentation the three-dimensional image into a plurality of regions on the basis of the original image data. In the region segmentation, a local thickness calculation is performed on the three-dimensional image to determine an index value indicating a size of an object included in the three-dimensional image, the three-dimensional image is segmented into a region indicated by the index value greater than a predetermined first threshold and a region indicated by the index value less than the first threshold, and each of the regions resulting from the segmentation is further segmented by the watershed algorithm.

Image processing method and recording medium

It is provided a technique capable of noninvasively and quantitatively evaluating the state of cultured three-dimensional cell-based structure. A method of evaluating a three-dimensional cell-based structure according to the present invention comprises: performing tomography of the cultured three-dimensional cell-based structure (step S); generating stereoscopic data indicating the three-dimensional shape of the three-dimensional cell-based structure based on image data acquired by the tomography (step S); and counting the number of structures isolated from each other in the three-dimensional cell-based structure based on the stereoscopic data (step S).

Growing community of inventors

Tottori, Japan

Tetsuya Ohbayashi