Fujitsu Corporation

Meiji Seika Kaisha, Ltd.

Tetsuya Matsushima

Kiyoaki Katano

Naoto Ohkura

Yukiko Hiraiwa

Masaharu Shiotani

Takehiro Yamamoto

Shigeki Suzuki

Yuuko Nakatani

Keiichi Murakami

Atsuo Iida

Takashi Tsuruoka

Kenichi Fushihara

Takayuki Usui

Chika Kikuchi

Kenichi Kanemoto

Kazue Sasaki

Tetsutaro Niizato

Mieko Nagasawa

Eriko Satoh

Kokichi Suzuki

Chidsuko Kuroda

Chizuko Kuroda

Hajime Hayashi

Takehiko Nishimura

Takuya Noda

Yutaka Fukui

Yuichi Sugiyama

A managing unit manages an identifier for identifying an authenticated container that is authenticated as a legitimate container. An inquiring unit inquires, before transferring a substance between containers, the managing unit whether both of the containers are the authenticated containers. An approving unit approves a transaction of the substance, upon acquiring a response from the inquiring unit saying that both of the containers are the authenticated containers.

Transaction quality system and quality assurance method

Disclosed are compounds represented by formula (I) which have triglyceride biosynthesis inhibitory activity in the liver and inhibitory activity against the secretion of apolipoprotein B-containing lipoprotein from the liver and particularly have excellent inhibitory activity against the secretion of apolipoprotein B-containing lipoprotein, are free from side effect of accumulation of lipids in the liver, and are useful for the treatment and prevention of hyperlipidemia and arteriosclerotic diseases. In formula (I), Rand Rrepresent alkyl, alkoxy, cycloalkyl, phenyl, alkenyl, alkynyl, or a five- or six-membered saturated or unsaturated heterocyclic ring, or Rand R, together with a nitrogen atom to which Rand Rare attached, may form a ring; Rand Rrepresent a hydrogen atom, alkyl, a halogen atom, hydroxyl, nitrile, alkoxycarbonyl, alkoxy, or carboxyl; or Rand Rmay be attached to each other to form &#x2014;(CH)&#x2014;, &#x2014;N&#x2550;CH&#x2014;, &#x2014;CH&#x2550;N&#x2014;, or &#x2014;(Calkyl)C&#x2550;N&#x2014;; A, D, E, and G each represent a carbon atom, or any one of A, D, E, and G represents a nitrogen atom with the other three each representing a carbon atom; Q represents a nitrogen atom or a carbon atom; Y represents a group represented by formula (II) wherein X represents a hydrogen atom, group &#x2014;C(&#x2550;O)N(R)Ror group &#x2014;C(&#x2550;O)OR, Ris absent or represents a bond, an oxygen atom, a sulfur atom, &#x2014;SO&#x2014;, &#x2014;SO&#x2014;, &#x2014;CH&#x2014;CH&#x2014;, or &#x2014;CH&#x2550;CH&#x2014;, and Rand Rrepresent a hydrogen atom, alkyl, alkoxy, a halogen atom, or hydroxyl; and Z represents &#x2014;(CH)&#x2014;, &#x2014;O&#x2014;(CH)&#x2014;, or &#x2014;C(&#x2550;O)NH&#x2014;(CH)&#x2014;

Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same

Disclosed are compounds represented by formula (I) which have triglyceride biosynthesis inhibitory activity in the liver and inhibitory activity against the secretion of apolipoprotein B-containing lipoprotein from the liver and particularly have excellent inhibitory activity against the secretion of apolipoprotein B-containing lipoprotein, are free from side effect of accumulation of lipids in the liver, and are useful for the treatment and prevention of hyperlipidemia and arteriosclerotic diseases. In formula (I), R and R represent alkyl, alkoxy, cycloalkyl, phenyl, alkenyl, alkynyl, or a five- or six-membered saturated or unsaturated heterocyclic ring, or R and R , together with a nitrogen atom to which R and R are attached, may form a ring; R and R represent a hydrogen atom, alkyl, a halogen atom, hydroxyl, nitrile, alkoxycarbonyl, alkoxy, or carboxyl; or R and R may be attached to each other to form &mdash;(CH ) &mdash;, &mdash;N&boxH;CH&mdash;, &mdash;CH&boxH;N&mdash;, or &mdash;(C alkyl)C&boxH;N&mdash;; A, D, E, and G each represent a carbon atom, or any one of A, D, E, and G represents a nitrogen atom with the other three each representing a carbon atom; Q represents a nitrogen atom or a carbon atom; Y represents a group represented by formula (II) wherein X represents a hydrogen atom, group &mdash;C(&boxH;O)N(R )R or group &mdash;C(&boxH;O)OR , R is absent or represents a bond, an oxygen atom, a sulfur atom, &mdash;SO &mdash;, &mdash;SO&mdash;, &mdash;CH &mdash;CH &mdash;, or &mdash;CH&boxH;CH&mdash;, and R and R represent a hydrogen atom, alkyl, alkoxy, a halogen atom, or hydroxyl; and Z represents &mdash;(CH ) &mdash;, &mdash;O&mdash;(CH ) &mdash;, or &mdash;C(&boxH;O)NH&mdash;(CH ) &mdash;.

Nitrogen-containing heterocyclic compounds and benamide compounds and drugs containing the same

Phosphonic acid derivative having inhibitory activity against carboxypeptidase B

Nitrogen-containing heterocyclic compounds and therapeutic agents for hyperlipidemia comprising the same

Phosphonic acid derivatives having carboxypeptidase b inhibitory activity

Nitrogenous heterocyclic compounds and hyperlipemia remedy containing the same

There is provided an ultrasonic diagnostic apparatus in which transmission of ultrasonic waves into the subject and reception of the ultrasonic waves reflected within the subject are repeatedly performed to obtain a plurality of sequentially continued frames of image data, and a dynamic image is displayed in accordance with the image data thus obtained. According to the ultrasonic diagnostic apparatus, image data, which is transmitted to a storage unit for the purpose of an average arithmetic operation for the successive frame K+1, is selected for each pixel I from between two types of image data of an averaging image data B (K, I) after an average arithmetic operation processing and a new frame of image data A (K, I) before the average arithmetic operation processing. Thus, both the reduction of noises and the tracking ability to the movement are implemented with greater satisfaction.

Ultrasonic diagnostic apparatus and filter to obtain sequential frames

An ultrasonic diagnostic apparatus in which ultrasonic waves are transmitted into the subject, the ultrasonic waves reflected within the subject are received to obtain received signals, and an image is produced in accordance with the received signals thus obtained. Several reception scanning lines are formed in a transmission ultrasonic beam. Several images thus obtained are superimposed on one another or combined together. Using this device deterioration of the picture quality due to multiple reflections or multiple echoes is prevented.

Ultrasonic diagnostic apparatus

An acoustic imaging system includes pairs of variable gain amplifiers for deriving essentially pairs of signals from respective signals generated in respective ultrasonic vibrators and the pairs of signals are superimposed on each other in a time difference corresponding to a phase angle of .pi./2 in frequency of ultrasonic waves. Amplification factors of the variable gain amplifiers are controlled so that the desired phase shift of the superimposed signals is obtained to attain dynamic focusing. Another acoustic imaging system includes a switch circuit having a two stage matrix switches construction that performs matrix switch functions in a smaller number of switch elements. Still another acoustic imaging system includes constituents for the aforementioned phase control for fine adjustment of delay time, the aforementioned switch circuit for rough adjustment of delay time, and variable gain amplifiers that perform smooth switching of the delay time.

Acoustic imaging system

An ultrasonic diagnostic apparatus including ultrasonic transducers. The ultrasonic diagnostic apparatus performs calculations for respective ultrasonic transducers to determine at which focal position a signal having just been received by the transducers is reflected in accordance with a lapse of time from a time when ultrasonic waves are transmitted. A delay time of respective received signals obtained from the transducers are determined in accordance with the results of the calculations. According to the present invention, control data which determines the delay time is stored in a first stored apparatus, compensation data which compensates the control data is stored in a second storage apparatus. The control data and compensation data read out respectively from these first and second storage apparatuses are added to one another, and the delay time for transmission and reception is determined according to the sum of the control data and compensation data.

An ultrasonic wave beam former including: a ultrasonic wave probe (1) equipped with a plurality of transducers (2) for converting a ultrasonic wave signal to an electric signal for effecting a dynamic focus by multiplying each channel signal as an output signal from each of the transducers (2) by a reference wave signal having the phase which is dynamically adjusted for each channel, and adding together each after-multiplication signal after the multiplication through a delay line (3), characterized in that at least two kinds of reference signals having mutually different frequencies are provided for each of the channels and at least two multipliers (10) are also provided;

Ultrasonic beam forming system

Disclosed is an ultrasonic receiving apparatus for use with an ultrasonic diagnosis system, the apparatus containing digital delaying means and/or digital adding means. The delaying means provides delays of sufficiently high accuracy using a clock signal of a reasonably high repeat frequency on a reasonable scale of circuit construction, while the adding means allows for larger probe aperture.

Ultrasonic receiving apparatus

An amplitude variable pulse generator is provided with two voltage supply sources. The first voltage source supplies a variable voltage which determines the amplitude of the output pulse. The second voltage source is a fixed or constant voltage source which provides a voltage lower in value than the first voltage. The second voltage source quickly pulls up a voltage between a drain and a source of a switching MOSFET, which generates the output pulse, by providing a charging voltage for an output capacitance of the MOSFET. By doing so, the output capacitance of the MOSFET is quickly reduced, and the trailing edge of the output pulse is not rounded even when the variable voltage is low. As a result, the waveform of the output pulse is not rounded for a very small amplitude pulse. Resolution of a supersonic wave device especially a supersonic diagnostic device is thereby improved.

Amplitude variable pulse generating circuit

Growing community of inventors

Yokohama, Japan

Tetsuya Matsushima