Canon Kabushiki Kaisha

Kyoto University

Tetsuya Matsuda

Tetsuya Yano

Hidetoshi Tsuzuki

Teruyuki Kondo

Hidehito Tochio

Yoshinori Tomida

Kimihiro Yoshimura

Katsuaki Kuge

Hiroki Miura

Hiroshi Tsujita

Zainul Abedin Siddique

Shingo Matsuki

Michiko Narazaki

Masato Minami

Fumio Yamauchi

Shinsuke Sando

Yasuhiro Aoyama

Masahiro Shirakawa

Megumi Nakao

Hisatsugu Yamada

Yoshinori Hasegawa

Yu Kimura

Akira Amano

Hiroshi Date

Junko Tokuno

Toyofumi Yoshikawa

Fuminori Sugihara

A machine learning device includes: a generation unit generating a first shape model representing a shape of an object before deformation and a second shape model representing a shape of the object after the deformation based on measurement data before and after the deformation; and a learning unit learning a feature amount including a difference value between each micro region and another micro region that constitute the first shape model, and a relation providing a displacement from the each micro region of the first shape model to each corresponding micro region of the second shape model.

Machine learning device, estimation device, non-transitory computer readable medium, and learned model

As a substance used as a contrast agent for a method of nuclear magnetic resonance analysis or a method of magnetic resonance imaging, a substance with high selectivity and high sensitivity was demanded. According to the present invention, when a polymer having, in a side chain thereof, a sequence of aH&#x2014;C&#x2014;N,H&#x2014;N&#x2014;C orH&#x2014;C&#x2014;C bond, that is, a structure labeled with stable isotopes ofC andN, is used, the abundance of such a sequence in one molecule can be increased, and hence, high selectivity and higher sensitivity can be attained when used as a contrast agent.

Polymer, contrast agent for nuclear magnetic resonance analysis or magnetic resonance imaging using the polymer, compound and method of nuclear magnetic resonance analysis and method of magnetic resonance imaging using the polymer

A core of a cyclic structure represented by (&#x2014;N&#x2014;(CH)&#x2014;)is bonded to a dendrimer-type side chain with a specific branched structure at all nitrogen atoms in the core to produce a compound with a specific structure for producing a metal complex that exhibits a T1-reducing effect, and the resulting compound is coordinated to a metal ion that has a T1-reducing effect to obtain a metal complex that exhibits an excellent T1-reducing effect which is useful as an effective component of an MRI contrast agent and an MRI contrast agent using the same.

Aza metal complexes

AZA compounds and production method thereof, and metal complexes as MRI contrast agents

A method for analyzing motion of an imaging target by means of tagged MR images includes performing, on the same motion of an imaging target, N(N: positive integer not less than 2) times of cine imaging by means of different tag patterns, to obtain Npieces of time-series tagged MR images taken for a plurality of time phases in the motion of the imaging target, arranging Npieces of pixel values of the same pixel in the Npieces of tagged MR images at each time phase into a pixel value sequence having a length Nfor the corresponding pixel, and analyzing the motion of the imaging target in the time-series tagged MR images by detecting pixels whose pixel value sequences constitute the same code sequence in different time phases. Each of the tag patterns is formed such that the pixel value sequence constitutes a predetermined code sequence.

Method of analyzing motion of imaging target by means of tagged MR images, and MRI device

Growing community of inventors

Kyoto, Japan

Tetsuya Matsuda