Kureha Kagaku Kogyo Kabushiki Kaisha

Tetsuya Hotta

Chikao Yoshikumi

Yoshio Kawai

Minoru Ohara

Satoru Enomoto

Saburo Ueno

Kiyoshi Inokuchi

Keizo Sugimachi

Hidenobu Kai

Yoshio Omura

Akira Sogawa

Toshiharu Shirakami

A device for radio-frequency hyperthermia having

Device for hyperthermia

An endotract antenna used for hyperthermia treatments. A microwave radiation antenna is surrounded by a balloon-like member made of a thin polymeric film. Tubes for feeding and draining a cooling liquid to and from the inside of the balloon-like member enable the device to effectively warm an endotract lesion such as a tumor by effectively supplying the energy of the microwaves emitted from the antenna to the endotract lesion.

Endotract antenna device for hyperthermia

Disclosed in this invention are protein-bound polysaccharides having antitumor activities. The polysaccharides have molecular weight within a specified range and present a pattern of color reaction peculiar to the saccharides as well as a pattern of color reaction characteristic of amino acids and peptide bonds. The proton nuclear magnetic resonance spectra of the polysaccharides show peculiar absorption bands. The ratio of the polysaccharide portion to protein portion in the polysaccharides is within a specified range. The protein-bound polysaccharides can be obtained by extraction of the mycelia and/or fruit bodies of fungi belonging to Coriolus of Polyporaceae of Basidiomycetes.

Protein-bound polysaccharides

A nitrogen-containing polysaccharide, which is obtainable by extracting mycelia of a fungus belonging to the genus Coriolus of Polyporaceae of Basidiomycetes with an aqueous solvent, is effectively used in treating a bacterial infectious disease due to the strain of the pathogenic bacterial species, which has come to be resistant to the treatment with conventional antibiotics.

Pharmaceutical composition comprising a nitrogen-containing

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Hoya, Japan

Tetsuya Hotta