Kyoto Prefectural Public University Corporation

Kataoka Corporation

Lsip, LLC

Kansai Technology Licensing Organization Co., Ltd.

Tetsuro Takamatsu

Yoshinori Harada

Ping Dai

Katsumasa Fujita

Noriaki Koizumi

Takeo Minamikawa

Eigo Otsuji

The present invention provides a method with which it is possible to directly induce nervous system cells efficiently and in a short amount of time. Because the method is easy to scale up and is not affected by the characteristics or background of the somatic cells used as material, the method enables the stable supply of nervous system cells. The nervous system cells obtained by the method are useful in various fields of research and healthcare.

Method for producing nervous system cells

The present invention provides a method of detecting nerves, including: step 1 of irradiating a sample with excitation light; step 2 of detecting Raman scattering light from the sample; step 3 of calculating an intensity ratio of a wave number within a specific range of the Raman scattering light detected in the step 2 or extracting a feature of the intensity ratio and subjecting the feature to multivariate analysis and/or statistical analysis; and step 4 of specifically displaying nerves containing unmyelinated nerves, using as an index the intensity ratio or a result from the multivariate analysis and/or the statistical analysis.

Method for nerve detection by raman scattering spectroscopy

The present invention provides a device for identifying a tumor site in a subject, the device spectroscopically detecting fluorescence of protoporphyrins present in the tumor site,

Tumor site or parathyroid gland identification device and method

The present invention provides a method for producing iPS cells, comprising reacting cells with at least one connexin inhibitor and at least one TGF&#x3b2; signaling inhibitor; iPS cells comprising at least one connexin inhibitor; an iPS cell inducer comprising at least one inhibitor selected from the group consisting of connexin inhibitors and TGF&#x3b2; signaling inhibitors; a medium for inducing iPS cells, comprising at least one inhibitor selected from the group consisting of connexin inhibitors and TGF&#x3b2; signaling inhibitors; and a kit for inducing iPS cells, comprising at least one inhibitor selected from the group consisting of connexin inhibitors and TGF&#x3b2; signaling inhibitors.

Induced pluripotent stem cells produced with a connexin inhibitor and a TGF-&#x3b2; signaling inhibitor

In an optical microscope, a pair of convergence/collimation lenses () are arranged in the common optical axis of a light beam directed toward a sample () being observed through an objective lens () and a light beam radiated or reflected from the sample to pass through the objective lens respectively. A means () varying the phase of the transmitting light beam is varied within a specified range is provided between these lenses so that the sample is irradiated while being focused at a depth corresponding to the phase at the wave front of the light beam entering the objective lens.

Growing community of inventors

Kyoto, Japan

Tetsuro Takamatsu