Ss Pharmaceutical Co., Ltd.

Life Science Laboratories Co., Ltd.

Tetsuro Ikekawa

Fumitake Shimada

Kazuo Uebaba

Akiko Ikekawa

Jong-Chol Cyong

EEM-S obtained by extracting with hot water or a lower alcohol at least one mushroom selected from among ver. , blanc du pays, and , treating the obtained extract by the molecular sieve method and thus eliminating low-molecular-weight and high-molecular-weight fractions: and preparations thereof. This EEM-S exerts physiological effects such as anticancer, immunopotentiating, antioxidative, hypotensive and hypoglycemic effects.

Physiologically active substance EEM-S originating in mushrooms, process for producing the same and drugs

A 13-propylberberine salt, which is represented by the following general formula (I): ##STR1## wherein X.sup.- means HSO.sub.4 or H.sub.2 PO.sub.4, has strong inhibitory effect against secretion, good stability and high water solubility. Its effects are shown promptly after its oral administration.

Growing community of inventors

Chiba, Japan

Tetsuro Ikekawa