Hitachi, Ltd.

Kyowa Hakko Kogyo Co., Ltd.

Kyowa Hakko Bio Co., Ltd.

Sumika Enviro-science Co., Ltd.

Tetsuo Nakano

Masahiro Iwamura

Hideo Maejima

Shigeya Tanaka

Masato Ikeda

Kozaburo Kurita

Tatsumi Yamauchi

Hiroshi Shimizu

Ikuro Masuda

Takehisa Hayashi

Toshihiko Gotoh

Toshio Doi

Naohiro Ozawa

Kentaro Hanma

Satoru Furukawa

Seiji Okunomiya

Yoshiyuki Kuratsu

Eitora Yamamura

Tomoki Azuma

Nozomu Kamada

Taei Kubota

Yuichi Kobayashi

Hideo Kawabe

Mitsuhiro Kitani

Kuniki Kino

Satoshi Mitsuhashi

Katsuya Miyata

Kazuo Koide

Masahiro Ueno

Noboru Kiyama

Mikiro Hayashi

Atsuo Hotta

Hirokazu Aoshima

Mikio Yamagishi

Yutaka Takano

Kazuyuki Okamoto

Tatsuo Nojiri

Shinya Imanishi

Masami Takada

Motokazu Nakayama

Keiichirou Inui

Kouichi Waki

Kenji Tanaka

Hisashi Tada

Yuichi Takano

Mariko Shitashige

The invention provides a double-stranded ribonucleic acid (dsRNA) having a chain length suitable for simultaneously showing low toxicity and high function in the use of an adjuvant and the like, and resisting variation of chain length even when subjected to a heating and cooling treatment, or a salt thereof; an immune potentiator, adjuvant, pharmaceutical product and the like containing the dsRNA and the like; and a production method of such dsRNA and the like. The invention is characterized in that the weight average chain length of two or more single-stranded ribonucleic acids (ssRNAs) constituting the first chain constituting dsRNA is not more than &#xbd; of the weight average chain length of one ssRNA constituting the second chain.

Double-stranded ribonucleic acid for adjuvants

Provided is a communication system capable of enhancing convenience for remotely operating a movable-body-mounted apparatus mountable in a movable body such as a vehicle. For example, a communication system includes a movable-body-mounted apparatus including: a movable body information storage part which stores movable body information including a received signal quality of a radio wave used for communication to/from a center server and information on a vehicle; a separation determination part which determines whether or not a user who moves along with the vehicle is separated from the vehicle; and a movable body information notification part which notifies the user of the movable body information stored in the movable body information storage part when the separation determination part determines that the user is separated from the vehicle.

Communication system, movable-body-mounted apparatus, terminal device, and center server

This invention relates to an allergen-reducing composition comprising a hydroxyproline derivative, a polymer thereof, or a salt of such a derivative or polymer, which is capable of reducing the allergenicity of mites, pollens, or other allergens and is capable of imparting functions of reducing allergenicity to fibers or textiles such as a carpet, a tatami mat, a bed cloth, a curtain, clothing, a stuffed animal, a mask, a filter material, or a dust bag for an electric vacuum cleaner without discoloration; and a method for reducing allergens using such composition.

Composition and method for reducing allergen

The present invention provides a polypeptide which has: (i) an amino acid sequence wherein one or more amino acid residues are substituted in the region at positionstofrom the N terminus of the amino acid sequence shown in SEQ ID NO: 1; or (ii) an amino acid sequence wherein one or more amino acid residues are substituted in the region at positionstofrom the N terminus of the amino acid sequence shown in SEQ ID NO: 1 and one or more amino acid residues are deleted, substituted or added in the region at positionstoorto; and which has N-acetylglutamate kinase activity.

Process for producing L-arginine, L-ornithine or L-citrulline

Attempts are made to provide a novel transaldolase gene; a polypeptide encoded by this gene; a recombinant DNA obtained by integrating this gene; a microorganism carrying this recombinant DNA; and a process for producing an aromatic amino acid, an aromatic vitamin, L-histidine, riboflavin, a nucleic acid, a nucleic acid-associated substance, a novel saccharide, etc. by using the above microorganism. As the results of extensive studies, a novel transaldolase gene is isolated from chromosomal DNA of a microorganism belonging to the genusas a DNA fragment complementary to the requirement for shikimic acid of a transketolase defective variant obtained as a variant with the requirement for shikimic acid belonging to the genus. Further, a recombinant DNA containing this gene is constructed and transferred into a host microorganism, thereby achieving the objects as described above.

Transaldolase gene

In semiconductor integrated circuit device and microprocessor including at least one functional circuit block, the start of operation of the functional circuit block is detected prior to the start of operation, the functional circuit block for which the start of operation has been detected is activated prior to the start of operation and inactivated after the termination of operation.

Low power consumption semiconductor integrated circuit device and microprocessor

An industrially more advantageous method for the production of metabolites biologically synthesized via phosphoribosyl pyrophosphate (PRPP) is provided, making use of metabolically modified strains in which transketolase activity is deficient or reduced in comparison with the parent strain.

Method for producing metabolites biologically synthesized via phosphoribosyl pyrophosphate

Low power consumption semiconductor integrated circuit device and

The timing of digital signal sampling at a receiver is continuously adjusted relative to a master clock used to initiate sending, by controlling a phase difference between the receiver sampling clock and the master clock in accordance with feedback of an error signal determined by detecting deviation of sampling clock timing from desired reference timing during both start-up operation and normal operation. Propagation delay scattering in the individual devices is compensated for by setting the sampling clock at a desired reference timing at start-up. Propagation delay scattering caused by fluctuation during device operation is compensated for by detecting the deviation of the sampling clock timing from reference timing based on received digital signals during normal operation and then continuously correcting the sampling clock timing on the basis of the detection result.

Data transfer system and method

Disclosed is a process for producing L-leucine which comprises culturing in a medium a microorganism belonging to the genus Escherichia and having resistance to a leucine analogue and an ability to produce L-leucine, allowing L-leucine to accumulate in the culture, recovering L-leucine therefrom.

Process for producing L-leucine

Data transfer system and method including tuning of a sampling clock

Disclosed is a process for producing an L-amino acid which comprises culturing a microorganism belonging to the genus Escherichia, having resistance to 2-ketobutyric acid and ability to produce the L-amino acid in a medium until the L-amino acid is accumulated in the medium, and recovering the L-amino acid therefrom.

Process for producing L-amino acid

The invention aims at selecting a recording sheet discharge mode in accordance with user's priority of printing speed or printed image quality. In the thermal transfer printer, when discharge concurrent with printing is selected, a microcomputer operates to rotate a mode motor to close a transport passage between a guide member and a platen roller by means of a sheet discharge plate. Starting printing by rotating the platen roller in this state, the leading end of a recording sheet is delivered to a discharge opening, which is defined by the guide member and a guide plate, and introduced between sheet discharge rollers and idler rollers. When separate discharge after printing is selected, the microcomputer starts printing without rotating the mode motor. The sheet discharge plate closes the discharge opening defined by the guide member and the guide plate. The leading end of the recording sheet is delivered to the transport passage between the guide member and the platen roller.

Thermal transfer printer

Growing community of inventors

Tokyo, Japan

Tetsuo Nakano