Theocorp Holding Company, LLC

Other

Biomedical Development Corporation

Tetsuo Nakamoto

Arman Sadeghpour

Alexander U Falster

William Bruce Simmons, Jr

William B Simmons, Jr

Compositions and methods for reducing oral sensitivity, increasing the systemic health of a mammal, occluding a dentinal tubule within a mammalian tooth, and/or depositing a precipitate on the surface of a mammalian tooth are provided, said compositions comprising theobromine (3,7-dimethylxanthine, the principal alkaloid in).

Compositions containing theobromine and their use in treating tooth hypersensitivity

Compositions and methods for culturing cells with theobromine are provided, as well as cells derived thereby. Theobromine compositions for enhancing bone formation, increasing bone density, increasing interconnections of internal bone, increasing bone mass, treating cartilage and/or bone defects, increasing fetal birth weight, preventing tooth decay, remineralizing a tooth surface, treating dentine hypersensitivity, and application to a bone site to promote new bone growth at the site are also provided.

Theobromine compositions useful for increasing fetal weight gain and enhancing bone properties

Provided are compositions and methods for preventing dental caries, as well as aqueous compositions and methods for improving the mechanical strength of teeth.

Methods and compositions to improve mechanical resistance of teeth

Methods comprise contacting apatite-forming-systems with partially alkylated xanthines. The methods include pharmaceutical applications of partially alkylated xanthines to mitigate the effects of hard tissue diseases. Products comprise apatite formed from apatite-forming-systems contacted with partially alkylated xanthines.

Apatite-forming-systems: methods and products

Products comprise apatite formed from apatite-forming-systems contacted with partially alkylated xanthines.

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Kenner, LA, United States of America

Tetsuo Nakamoto