Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai

The University of Tokyo

Microbial Chemistry Research Foundation

Tetsuo Akiyama

Yasuhiko Muraoka

Tomio Takeuchi

Yoshikazu Takahashi

Masatoshi Abe

Masa Hamada

Hiroshi Naganawa

Keita Nakamura

Shohei Sakuda

Shigeko Harada

Ikuko Kurata

The present invention relates to provide an aflatoxin production inhibitor that inhibits aflatoxin production specifically and efficiently, is highly safe, and is practical, and an efficient production method thereof; and a method for controlling aflatoxin contamination that uses the aflatoxin production inhibitor, specifically relating to an aflatoxin production inhibitor that includes at least one of a dioctatin represented by the following formula (I) and a derivative thereof, as an active ingredient: where, in the formula (I), R represents one of hydrogen and a methyl group.

Aflatoxin production inhibitor and method for controlling aflatoxin contamination using the same

Sulphostin analogue and process for producing sulphostin and its analogue

This invention provides a physiologically active substance having a strong dipeptidyl peptidase IV inhibitory activity. The physiologically active substance sulphostin is obtained by culturing a microorganism belonging to the genus Streptomyces and having an ability to produce the physiologically active substance sulphostin, producing and accumulating this substance in the cultures, and harvesting it from the cultures.

Physiologically active substance sulphostin, process for producing the same, and use thereof

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Tokyo, Japan

Tetsuo Akiyama