Kagoshima University

Sumitomo Bakelite Company Limited

Jnc Corporation

Teruto Hashiguchi

Masao Fukushima

Hideyuki Shimaoka

Hiroki Abe

Ikuro Maruyama

Midori Abe

Taichi Aihara

Kenji Tanaka

Shoji Natsugoe

Yasuto Uchikado

Lyang-ja Lee

Salunya Tancharoen

Hiroyuki Shinchi

Kota Igarashi

Kosei Maemura

Yuko Mataki

Ko-ichi Kawahara

Norichika Moriwaki

Masaru Sekijima

Ko-Ichi Kawahara

Lyang-Ja Lee

The present invention provides an inhibitor of an autoimmune response to a periodontal bacterial enzymatic degradation product of keratin in gingival epithelium in a mammal having a periodontal bacterium in the oral cavity, containing a substance having affinity to the keratin or a degradation product thereof and/or a substance having affinity to an autoantibody to the degradation product, an agent for the prophylaxis and/or treatment of a periodontal disease and/or a complication thereof; a RANKL expression inhibitor containing a substance having affinity to the keratin or a degradation product thereof; and a method of diagnosing a periodontal disease including detecting the keratin or a degradation product thereof and/or an autoantibody thereto.

Periodontal-disease-specific peptide, and treatment and diagnosis of periodontal disease using same

As a result of collecting blood from pancreatic cancer patients, esophageal cancer patients, and stomach cancer patients, and conducting mass spectrometry on N-linked sugar chains in the plasmas, sugar chains whose abundances are significantly different from those of healthy subjects have been successfully identified from the blood samples of the cancer patients.

Method for inspecting gastroenterological cancer by utilizing N-linked sugar chain

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Kagoshima, Japan

Teruto Hashiguchi