Other

Saga University

Teruo Inoue

Hiroshi Oda

Yoshihiro Urade

Nobuyuki Sato

Kosuke Seiki

Hiroshi Nakajima

Yoshio Uehara

Koichi Node

The present invention is directed to a method for evaluating whether coronary artery disease has progressed in a patient previously diagnosed as having the disease, wherein the method includes: (a) obtaining a biological sample from the patient at a first time point and a second time point; (b) detecting the level of platelet-derived microparticles (PDMPs) or a fragment thereof, in the first time point sample and the second time point sample with an antibody to PDMPs or a fragment thereof; wherein an increase in a level of the PDMPs in the second time point sample in comparison to a level in the first time point sample is indicative of progression of coronary artery disease.

Platelet-derived microparticles as a novel diagnosis maker for a cardiovascular disease

The present invention provides a method for predicting restenosis following coronary intervention by measuring human lipocalin-type prostaglandin D synthase (L-PGDS) in a body fluid sample. More particularly, this method comprises measuring the L-PGDS concentration in the sample and predicting restenosis following coronary intervention by using a change therein as an indicator.

Method for restenosis following coronary vessel intervention

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Saitama, Japan

Teruo Inoue