The University of Tokyo

Terumo Kabushiki Kaisha

Nippi Corporation

Teru Okitsu

Shoji Takeuchi

Keisuke Tanaka

Osamu Hayashida

Tetsuro Kawanishi

Shunji Hattori

Hideaki Shibata

Yukiko Matsunaga

Naoko Teramura

Katsumasa Iijima

Yun-Jung Heo

Recombinant collagenases with a stable specific activity and enzyme agents for cell and tissue dissociation such a recombinant are provided. The recombinant collagenase is derived from-derived collagenase is characterized by having, from the N terminus to the C terminus, a collagenase catalytic domain, a linker region sequence, and a prepeptidase C terminal domain, which-derived recombinant collagenase does not comprise at least the prepeptidase C terminal domain. The obtained recombinant collagenase has a high and stable specific activity.

[object Object]

To provide a fluorescent hydrogel having superior detectability of saccharides such as glucose and minimal invasiveness, a method for producing the same, and a sensor for measuring saccharides using the same. A florescent hydrogel having a structure represented by the following chemical formula 1, a method for producing the same, and a sensor for measuring saccharides using the same. 

Fluorescent hydrogel and method for producing the same, and sensor for measuring saccharides using the same

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Tokyo, Japan

Teru Okitsu