Becton Dickinson and Company Limited

Terry J Amis

J Bruce Pitner

Douglas Byron Sherman

John D DeNuzzio

Steven Keith

Kristin Weidemaier

Ross Jacobson

Javier Alarcon

Christopher C Herdman

A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. A sensing element is attached to the distal end of an optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the optical conduit and sensing element may be housed within a cannulated bevel.

Fiber optic device for sensing analytes and method of making same

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Cary, NC, United States of America

Terry J Amis