Abbott Laboratories Corporation

Other

Eastman Chemical Company

Abbott Gmbh & Co Kg

Terrence B Mazer

Charles Edwan Sumner, Jr

Scott Donald Barnicki

James P Perry

Joseph E Walton

Ronita K Geckle

Andre Daab-Krzykowski

Carl Joseph Piontek

Normanella T DeWille

Paul W Johns

Gregory A Snowden

Michael A Chandler

Robert L Joseph

William Guy Pierson

Susan Beth Duel

John D Suh

Christy A Nardelli

John J Kropczynski, Jr

Arthur J Hogarth

Thomas D Loughrin

Mark Anthony McCamish

Frederick Oliver Cope

Bonnie Chandler Abbruzzese

Thomas Walter Osip

Louis I Ndife

Paul S Anloague

Neile Edens

Catherine D Johnson

Ernest W Richards

Karin M Ostrom

James N Chmura

Lonnie R Drayer

Marti S Bergana

Robert A Shalwitz

Charles A McCombs

Stephen J DeMichele

James M Simpson

Joseph P Schaller

Thomas Kessler

Tapas Das

Kent Lee Cipollo

Stephen Joseph Demichele

Frank S Walczak

Christopher A Cox

David R Wolf

Diane M Garcia

Robert John Ragan

Maureen Elizabeth Geraghty

Fu-i Mei

Rhonda L Cole

Kati E Shearer

Glenn A Meyer

Robert Alan Miller

Frank A Murawski

Seiji Aoyagi

Sherri A Walker

Nickki L Parlet

Larry G Tucker

Daniel Hamilton

Leona M Pickett

Barbara S Arnholt

Kelley J Lowe

Shie-Ming Hwang

Jeffrey H Baxter

Normanella Dewille

Daniel L McKamy

David C Ulstad

Steven Neal Anderson

James C Phillips

Ulrich Westedt

Amy L Marchio

Stephen J Kirchner

David V Diodato

Jeffery Wayne Liebrecht

Dennis V Boruszewski

Rhonda Cole Walsh

Michael V Walsh

William J Nelson

Harold W Keller

Monty L Evans

Laura A Pease

Jeffrey G Morris

Wilson G Zeitler

Vikkie Mustad

Allison Ogilvie

Douglas J Wearly

Michelle Marie Smith

Steven R Dimler

Judith R Atkinson

Daniel Zevchik

Mark D Green

Edrick L Candler, Jr

Keith E Rushlow

Anand Seth

Dennis L Raube

Francis J Cipriano

Edward H Parke

Emily Stepp

Amanda L Smeller

Michael Joseph Antinone

Disclosed are nutritional compositions, and methods of using and making the nutritional compositions, that include calcium beta-hydroxy-beta-methylbutyrate and protein. The calcium beta-hydroxy-beta-methylbutyrate is in sequestered or ion-exchanged form to reduce the interaction of the calcium with the protein in the nutritional composition and improve the overall stability of the nutritional composition.

Nutritional compositions including calcium beta-hydroxy-beta-methylbutyrate, protein and low levels of electrolytes

Disclosed are substantially clear nutritional liquids comprising protein and calcium HMB wherein soluble protein represents from about 65% to 100% by weight of total protein. The liquids have a pH of from about 2.8 to about 4.6 and may be manufactured as a hot fill product. The substantially clear nutritional liquids may also have a weight ratio of calcium HMB to soluble calcium of from 4.5:1 to 7.3:1. In some embodiments, the substantially clear nutritional liquids are substantially free of fat, and may optionally include isomaltulose and/or beta alanine.

Substantially clear nutritional liquids comprising calcium HMB and soluble protein

Pouch

Disclosed are compositions and corresponding methods for treating fibrocystic breast disease or other breast-related disease or condition. The compositions comprise, per serving or dose, from zero to about 400 &#x3bc;g selenium, from about 100 mg to about 6000 mg gamma linolenic acid, and about 0.15 mg to about 5 mg iodine, with nutritional embodiments further comprising one or more of protein, fat, carbohydrate, vitamins, and minerals and providing from about 50 to about 1000 kcal of energy per severing or dose. Also disclosed are in-vitro studies showing that certain combinations of gamma linolenic acid, iodine, and/or selenium may 1) inhibit breast cancer or fibrocystic cell proliferation, 2) reinforce the function of tight junctions of endothelial cells and of mammary epithelial cells in estrogen-sensitive conditions, and 3) reduce the risk of vascular invasion by breast cancer cells.

Compositions for improving breast health in women

Disclosed are compositions, including low-calorie beverages or liquids, comprising isoleucine, leucine, valine, cysteine, and methionine, in specified amounts, weight ratios, or both. The compositions are especially useful in treating individuals afflicted with impaired glucose tolerance or diabetes.

Amino acid composition for improving glucose tolerance

Disclosed are nutritional compositions and methods for preparing the compositions, comprising fat, protein, and carbohydrate, including a combination of curcumin, demethoxycurcumin, and bisdemethoxycurcumin, which combination is solubilized in a polar oil having an HLB value of from about 0.7 to about 14 wherein the weight ratio of the bisdemethoxycurcumin to the curcumin is from about 1:1 to about 1:7 and the weight ratio of the bisdemethoxycurcumin to the demethoxycurcumin is from about 1:1 to about 1:2.5. The composition provides a selected ratio of curcuminoids having improved biological activity, bioavailability, and reduced color impact.

Methods for making nutritional compositions comprising curcuminoids

The present invention provides a food product comprising: a formed reduced glycemic response cereal component; and a non-sticky reduced glycemic response sweetener coating over the formed cereal component, the sweetener coating comprising: a first sticky layer comprising at least about 30% fructose (of the total sweetener coating); a second less sticky layer having a DE value of about 60 or less and comprising up to about 17% fructose and at least about 1% non-fructose carbohydrates (of the total sweetener coating); and third layer comprising crystalline fructose. The present invention also provides a process for forming the sweetener coating over the formed cereal component comprising the following steps: (a) providing a formed cereal component having thereon a first sticky layer comprising fructose; (b) forming over the first sticky layer a less stick second layer comprising non-fructose carbohydrates and optionally fructose; and (c) applying crystalline fructose over the second layer.

Controlled glycemic response sweetened cereal product

The present invention is directed to a method for alleviating mucositis, sassociated with radiation and chemotherapy, via the administration of an oral rehydration solution.

Methods for alleviating mucositis

Dosage form unit is provided to deliver one or more beneficial agents into a fluid, such as liquid enteral nutritional product. The dosage form unit includes a core containing at least one beneficial agent, preferably a marker dye, which is dispersible in the fluid. The core also contains a compatible binding agent to bind the beneficial agent together. Additional components of the core may include a plasticizer, a standard flow agent, a lubricant, additional tableting aids and at least one hydrophilic agent. A latex coating encases the core. The latex coating includes a mixture containing a substantially hydrophobic base material, preferably formed from an emulsion of cellulose acetate microspheres, which is capable of defining a matrix-type membrane, and at least one hydrophilic component being dispersible in the fluid. A dispersible beneficial agent is preferred as one of the hydrophilic components of the latex coating to allow immediate release of the beneficial agent therefrom. A method of making the dosage form unit also is provided.

Sustained release dosage form unit having latex coating and method of making the same

This invention is directed to a low pH nutritional formula that contains high levels of macronutrients, vitamins and minerals. The pH of the enteral formula is from about 3.0-4.6 and delivers at least 25% of the RDI for selected vitamins and minerals in a 237 ml. serving. The enteral formula uses a stabilizing system comprising high methoxy pectin to stabilize the protein and a unique process to produce the formula.

Nutritionally complete low pH enteral formula

The present invention relates generally to a method of producing plant proteins for use in nutritional products that have reduced levels of phytoestrogens, manganese or nucleotides. More specifically, this invention is directed to a method of using ion exchange technology to remove phytoestrogens, manganese or nucleotides from plant proteins. This invention is also directed to the plant protein product resulting from the inventive process and to nutritional products that use the plant protein product as a source of amino nitrogen.

Plant protein for nutritional products and method of making same

This invention provides a composition comprising notochord and extracts thereof in therapeutic amounts. The invention more specifically relates to a method of treating arthritis in mammals, more particularly rheumatoid arthritis in humans through the enteral administration of notochord, notochord extracts or mixtures thereof. In a preferred embodiment, collagen obtained from sturgeon is enterally administered to a human at from 1.0 &mgr;g to 1.05 gms per day.

Method and product using sturgeon notochord for alleviating the symptoms of arthritis

An apparatus for altering characteristics of a fluid. The apparatus includes a canister having a side wall, a first end wall, and a second end wall defining a chamber therein. A beneficial agent is disposed in the chamber. The end walls define apertures therethrough. The apparatus further includes a tubing portion defining a first end portion constructed for connection to a fluid source and an outlet portion. The tubing portion also defines a canister-receiving portion intermediate the first end portion and the outlet portion. The canister-receiving portion defines a first fluid flow channel fluidly connecting the first end portion and the second outlet portion of said tubing portion. The canister-receiving portion also defines first and second fluid flow orifices therethrough. The canister-receiving portion is constructed to be selectively connectable to the canister such that fluid from the tubing portion can be selectively directed through the canister chamber, thereby causing the beneficial agent to become dispersed in the flowing fluid.

Apparatus for altering the characteristics of a fluid

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Reynoldsburg, OH, United States of America

Terrence B Mazer