Wisconsin Alumni Research Foundation

Terra Potocky

Ronald Thaddeus Raines

Samuel Helmer Gellman

Michael A Gelman

Naoki Umezawa

Disclosed are &#x3b2;-peptides and &#x3b2;-peptide conjugates that are capable of diffusing or otherwise being transported across the cell membranes of living cells. The &#x3b2;-peptides contain at least six &#x3b2;-amino acid residues, at leastsix of which are preferably &#x3b2;-homoarginine residues. It has been found that when pharmacologically-active agents are conjugated to these types of &#x3b2;-peptides, the resulting conjugates (also disclosed herein) are also capable of diffusing or otherwise being transported across the cell membranes of living cells, including mammalian cells.

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Terra Potocky