Pyng Medical Corp.

Other

Quantumcor, Inc

Gilhuly, Terence

Terence Gilhuly

Gregory Vincent Browne

Christopher Grant Denny

Werner Reinhard Simbeck

David Brian Bonar

Ji Zhang

Samuel Victor Lichtenstein

An apparatus and method for introducing portals into bone is described herein. An example apparatus for introducing portals into bone includes a handle, a base, and a driving member. The driving member can be made to project past the base by operating the handle. The base is detachable from the handle. The apparatus also includes a guide coupled at a first end to the handle and at a second end to the base. The base is detachably coupled to the guide. A base coupling detachably coupling the base to the guide includes an actuating member movable between a coupled configuration wherein the base is coupled to the guide and an uncoupled configuration wherein the base is released from the guide. The actuating member is arranged so that motion of the handle toward the base moves the actuating member from the coupled configuration to the uncoupled configuration.

Apparatus and methods for introducing portals in bone

An apparatus for introducing a bone portal into a bone is described herein. An example apparatus for introducing portals into bone includes a stylet and a handle. The stylet is configured to support an infusion tube assembly. The infusion tube assembly comprises a bone portal. The handle is drivingly coupled to the stylet by a release mechanism. The release mechanism comprises a bone probe that, in a first configuration, extends generally parallel to the stylet. The release mechanism is operative to uncouple the driving coupling between the handle and the stylet upon axial motion of the bone probe relative to the handle. The stylet and bone probe are movable apart from one another to a second configuration.

Apparatus for introducing portals in bone having transversely movable bone probe

Improved sensors and sensing methods for detection of Neuromuscular Blockade (NMB), for example to improve monitoring generally, as well as facilitate automated NMB drug administration. The methods, systems, devices, etc., herein can increase the quantity and quality of data available. The methods, etc., include translation between commonly available sensing types, use of partially saturated sensor measurements, use of a model of neurotransmitter storage and release and sophisticated use of more than one sensor simultaneously. These methods are aided by new sensors and methods of decreasing electrical noise. An implementation of the methods, systems, devices, etc., herein is automated drug delivery for NMB, whether through an advisor system or through with full computer control.

Sensors and sensing for monitoring neuromuscular blockade

Some introducer tools for bone portals have a handle coupled to a driving member by a force-limiting coupling. A bone portal comprising a bone-penetrating portion and a bone stop may be driven to a desired depth in bone when the force-limiting coupling allows application of force to the bone portal that is sufficient to drive the bone-penetrating portion of the portal into the bone but not sufficient to drive the bone stop significantly into the bone. Bone portals of various types are described herein. Various configurations for stylets suitable for use in introducing bone portals or otherwise penetrating bone and methods for inserting bone portals are also described herein.

Apparatus for introducing bone portals

Apparatus for introducing portals in bone having movable bone probe

Apparatus having release mechanism for introducing bone portals and related methods

The present invention relates generally to methods of modeling and handling of nonlinearities for application of automatic control to systems with high inter-process variance and nonlinearities. The variance and nonlinearities make these systems difficult to control. Variance is accounted for by replacing the mathematical model of the system with a more representative model from a modelset that may or may not be chosen based on characteristics of the system under test, and then adapting using recursive estimation techniques. Nonlinearities defined by threshold to response and maximal responses are incorporated into linear models relating accumulated inputs to response. Example implementations in relation to automated drug delivery for neuromuscular blocking drugs through warning, advisory and closed-loop control systems are discussed.

Modeling and control for highly variable and nonlinear systems

In this patent, mechanically simple and inexpensive to produce platforms for modification of a stroller such that an additional child or a pet or a package may be transported are taught.

Stroller platforms

An improved wireless electrosurgery instrument comprising at least one surface electrical contact for contactably coupling the wireless instrument to a remote power source through a coupling mechanism, wherein the coupling mechanism comprises an insulated electrical conductor running through a surgeon's glove and/or a surgeon's gown.

Growing community of inventors

Vancouver, Canada

Terence Gilhuly