Maxygen, Inc.

Codexis Mayflower Holdings, LLC

Teddy Chen

Phillip A Patten

Jeremy S Minshull

Claes Gustafsson

Linda A Castle

Robin A Emig

Sridhar Govindarajan

Richard John Fox

S Christopher Davis

Rebecca Lynne Gorton

Daniel Siehl

Anthony Cox

Ajoy K Roy

Steven Henry Bass

Madan M Paidhungat

David Lin

Thomas Bouquin

Daniel L Siehl

Amy Brideau-Andersen

Douglas Guptill

Ian J Sas

Jeremy Minshull

Phil Patten

Sridar Govindarajan

Ajoy Apt120 Roy

Rebecca Lynne Apt819 Gorton

Christopher S Davis

The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.

Methods, systems, and software for identifying functional bio-molecules

Methods, systems, and software for identifying functional biomolecules

The present invention provides evolved interferon-alpha polypeptides, and conjugates thereof, and nucleic acids encoding the polypeptides. The invention also includes compositions comprising these polypeptides, conjugates, and nucleic acids; cells containing or expressing the polypeptides, conjugates, and nucleic acids; methods of making the polypeptides, conjugates, and nucleic acids; and methods of using the polypeptides, conjugates, and nucleic acids.

Evolved interferon-alpha polypeptides

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Belmont, CA, United States of America

Teddy Chen