Belhaven Biopharma, Inc.

Qenm.com

Ted William Lanpher

Barry Bleske

Scott Lyman

David J Mishelevich

Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.

Dry powder formulations of epinephrine and associated methods

Nasally targeted dry powder compositions and methods for their use in the treatment of exposure to organophosphate compounds including chemical warfare agents and pesticides. Compositions include anticholinergic agents and cholinesterase reactivator agents used for primary treatment and vasoactive agents and benzodiazepines used for secondary treatment of exposure, and combinations of these agents. Compositions incorporate excipients and enabling agents such as permeation enhancers, and optimal sizing of active pharmaceutical ingredient particle size to improve drug delivery across the nasal mucosa, stability, and resistance to heat degradation. Packaging and configuration of devices for dry powder nasal compositions enable their use by non-medical personnel in civilian mass casualty or battlefield environments.

Intranasal composition of pharmaceutical countermeasures for chemical warfare nerve agents and accidental exposure to organophosphate pesticides

A method and system for capturing data and verifying the data accuracy, includes a structured document having defined regions dealing with different categories. Dictionaries specific to the categories are included to check the accuracy. of words and phrases in the various regions. Points are allocated to the entered data to facilitate subsequent decision making, and a facility is provided to maximize the accumulation of points by visually indicating regions that could potentially be filled in to increase points most effectively. Preferably data is entered orally by a user into a computer system, and transcribed using speech-recognition software. The user is prompted for data entry, and the prompting mechanism may follow a predefined pattern and speed, or be adjustable by the user, or be adjusted by the computer by monitoring past user behavior.

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Half Moon Bay, CA, United States of America

Ted William Lanpher