Zoecon Corporation

Ted A Baer

Gustave K Kohn

Richard J Anderson

Jeffrey N Labovitz

Scott G Broadbent

An improved process for preparing substituted amino acids and lower alkyl esters thereof, and intermediates therefor, comprising reacting a substituted aniline, HCN and an aldehyde to form a nitrile, converting the nitrile to an imidate salt with a strong acid and an alcohol, hydrolyzing in situ the imidate salt to the ester with addition of water, and optionally converting the ester to the salt or free acid. The acids are useful intermediates in the synthesis of pesticides.

Substituted amino acid process

The acid chlorides of N-substituted-2-aminocarboxylic acids are prepared by treating the carboxylic acids with phosgene in the presence of a catalytically effective amount of a water soluble tertiary amine, which acid chlorides are useful in the manufacture of insecticides.

Substituted acid chloride process

A novel process for the manufacture of .alpha.-ketocarboxylic acids which comprises the reaction of oximinohalide with cyanide ion to form oximinonitrile which is reacted with hydroxide ion to form oximinoacid and hydrolysis thereof to the .alpha.-ketoacid.

Process for preparing .alpha.-ketocarboxylic acids

The present invention relates to halo-substituted 2,2 dimethylcyclopropaneamides, useful as intermediates for the preparation of imidates having pesticidal properties.

Substituted 2,2-dimethylcyclopropaneamides

Novel imidates, intermediates therefor, synthesis thereof and the use of said imidates for the control of pests.

Cyclopropyl and phenylisobutylimidates

Phenoxy imidates

(6-Phenoxy-2-pyridyl) methyl esters of imidates

Synthesis of 2-(4-trifluoromethylphenylamino)-3-methylbutanoic acid and lower alkyl esters thereof, optionally ortho substitution on the phenylamino group, novel intermediates thereof, which are useful intermediates in the synthesis of pesticides.

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Palo Alto, CA, United States of America

Ted A Baer