Nihon Nohyaku Co., Ltd.

Tatsuyoshi Sugimoto

Akio Hokazono

Hitoshi Kurono

Kuniaki Taninaka

Takehiro Shimada

Masahiro Hayashi

Masahiro Shimosako

Minoru Katoh

A pharmaceutical composition for prophylactic and preventive of ketosis of livestocks which contains a dithia derivative represented by the general formula (I), ##STR1## wherein R and R' may be the same or different and are each individually a lower alkyl group, n is an integer of 0, 1 or 2; and A is a group of the formula, --CH.sub.2 --, ##STR2## (wherein M is a hydrogen atom or a salt-forming residue), --CH.dbd.CH--, --CH.sub.2 --CH.sub.2 --, ##STR3##

Pharmaceutical composition for prophylactic and preventive of ketosis of

Feed compositions containing a dithia derivative represented by the general formula: ##STR1## wherein R and R' are same or different lower alkyl groups, n is an integer of 0, 1 or 2, and A is --CH.sub.2 --. ##STR2## (wherein M is hydrogen or a salt-forming residue), --CH.dbd.CH--, --CH.sub.2 --CH.sub.2 --, ##STR3## are useful for improving meat qualities of livestock, poultry and fish as well as for strengthening the eggshell of poultry.

Feed composition

Dithiolane derivatives represented by the formula (I): ##STR1## wherein R.sup.1 is an alkyl group, a cycloalkyl group, an alkenyl group, an alkynyl group, a benzyl group or an alkoxyalkyl group and R.sup.2 is a cyano group, an alkylcarbonyl group, a benzylcarbonyl group, a phenylcarbonyl group, an alkoxycarbonyl group, a cycloalkyloxycarbonyl group, a benzyloxycarbonyl group, an alkenyloxycarbonyl group, an alkynyloxycarbonyl group or an alkoxyalkoxycarbonyl group, and an organic acid ester thereof; process for producing the same; and pharmaceutical composition for controlling liver diseases of human beings and animals containing the same.

Dithiolane derivative, process for producing the same and use thereof

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Hashimoto, Japan

Tatsuyoshi Sugimoto