Daiichi Sankyo Company, Limited

Tatsuya Nishi

Ryoko Kitazawa

Naoki Tanaka

Masashi Hasegawa

Takashi Ishiyama

Hiroshi Susaki

Yuichi Ochiai

Riki Goto

Yumi Nakamoto

The present invention provides a compound which enhances the production of erythropoietin. The present invention provides a compound represented by the formula (1) wherein R: an aromatic hydrocarbon ring group or an aromatic heterocyclic group; R: a hydrogen atom, an alkyl group, or a heterocycloalkyl group; R: a hydrogen atom or an alkyl group; A: a hydrogen atom or a hydroxy group; L: &#x2014;NHCO&#x2014; or &#x2014;OCH&#x2014;; and X: a nitrogen atom or &#x2550;CH&#x2014;.

(2-heteroarylamino) succinic acid derivatives

A compound of the general formula (I): [wherein, Rrepresents a halogen atom, or the like, Rrepresents a hydrogen atom, or the like, Rand R, each independently, represent a hydrogen atom, a Calkyl group, or the like, Rrepresents a hydrogen atom, a halogen atom, or the like, Rrepresents a hydrogen atom, a halogen atom, or the like, Rand R, each independently, represent a hydrogen atom, a halogen atom, or the like, Rand R, each independently, represent a hydrogen atom, a Calkyl group, Rand R, each independently, represent a hydrogen atom, a Calkyl group, or the like, X represents an oxygen atom, a group &#x2014;CH&#x2014;, or the like, Y represents a nitrogen atom, a group &#x2550;CH&#x2014;, or the like, and Z represents a nitrogen atom, or the like] or a pharmacologically acceptable salt thereof, which has an excellent suppressive action on platelet aggregation, and is useful for prevention and/or treatment of thromboembolism.

3-(biaryloxy)propionic acid derivatives for prevention and/or treatment of thromboembolic diseases

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Tokyo, Japan

Tatsuya Nishi