Daicel Chemical Industries, Ltd.

Merck Patent Gmbh

Nissan Chemical Industries Limited

Tatsushi Murakami

Michael Schulte

Dieter Lubda

Akihiro Nakanishi

Hiroo Matsumoto

Yoshio Ohara

Hirokazu Ikeda

Akito Ichida

Nanami Nishida

Hiroyasu Kanda

This invention provides a separating agent for optical isomers, which has high asymmetry recognition ability and can be used particularly at a high flow rate when used for the separation of the optical isomers, and a separation column for optical isomers having the same. This invention provides: a separating agent for optical isomers which is used for separation of optical isomers in a sample comprising the optical isomers, which is comprising a monolithic inorganic type carrier having a meso pore formed on an inner wall surface of a specific macropore, and a polysaccharide or a polysaccharide derivative supported on the monolithic inorganic type carrier, wherein the meso pore has a pore size of 6 to 100 nm; and a separation column for optical isomers in which the separating agent for optical isomers is held in a column tube.

Separating agent for optical isomers and separation column for optical isomers

Process for preparing optically active mevalonolactone compounds

A separating agent which comprises a polysaccharide derivative having an Mw/Mn (wherein Mw and Mn represent the weight-average molecular weight calculated as polystyrene and the number-average molecular weight calculated as polystyrene, respectively), which indicates the extent of molecular weight distribution, of 1 to 3. When liquid chromatography is effected using this separating agent as a column packing, the base line is highly steady, various types of solvents can be used as the eluent, and low-molecular polysaccharide derivatives are not eluted.

Separating agent

Separating agent for optical isomers

Separating agent for optical isomers and process for producing the same

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Hyogo, Japan

Tatsushi Murakami