Hemanext Inc.

New Health Sciences, Inc.

Boston University

University of California

University of Pittsburgh

Dartmouth College

The Administrators of the Tulane Educational Fund

Tatsuro Yoshida

Paul J Vernucci

Mark W Bitensky

Andrew Dunham

Jeffrey Karl Sutton

Samuel O Sowemimo-Coker

Rafael Cordero

Sergey S Shevkoplyas

Philip Keegan

Jancarlo Sarita

Narendran Renganathan

Michael Wolf

William J Federspiel

Michael Robert Zocchi

Brian Joseph Frankowski

Larry J Dumont

Jennie M Burns

Michael G Frank

Christopher V Gabel

Jure Derganc

Michael Zocchi

Angelo D'Alessandro

Philip Michael Keegan

Sergey Shevkoplyas

Mark Bitensky

Methods for prevention and reversal of inflammation.

Methods for managing adverse events in patients with inflammation

A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles. Oxygen and pathogen reduced blood compositions comprising CPAD and riboflavin having reduced hemolysis. Oxygen and pathogen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles.

Anaerobic blood storage and pathogen inactivation method

A blood storage container for the anaerobic storage of blood, having enhanced sealing methods and materials for the preservation of stored blood is provided.

Anaerobic blood storage containers

A blood storage system comprising: a collection vessel for red blood cells; an oxygen or oxygen and carbon dioxide depletion device; a storage vessel for red blood cells; tubing connecting the collection vessel to the oxygen or oxygen and carbon dioxide depletion device and the oxygen or oxygen and carbon dioxide depletion device to the storage vessel; and a gamma or X-ray irradiating device is used to irradiate red blood cells stored in the vessel, storing red blood cells under anaerobic conditions.

Irradiation of red blood cells and anaerobic storage

Methods for the reversal of hemorrhagic shock or hemorrhagic trauma. Methods for restoring mean arterial pressure to a normal range and reducing trauma adverse risks in a patient through the administration of oxygen reduced blood compositions.

Methods and treatment of trauma adverse events with oxygen reduced blood

A system and methodology for the preservation of red blood cells is described in which red blood cells are oxygen or oxygen and carbon dioxide depleted, treated and are stored in an anaerobic environment to optimize preparation for transfusion. More particularly, a system and method for extended storage of red blood cells from collection to transfusion that optimizes red blood cells prior to transfusion is described.

System for extended storage of red blood cells and methods of use

Method for transfusion medicine to reduce adverse events in transfusion patient populations based on underlying patient physiology. Methods for reducing the risk of an inflammatory response in a sickle cell patient in need of a blood transfusion.

Methods and treatment for reducing the risk of an inflammatory response

Methods and compositions for improved clinical outcomes for trauma patients receiving whole blood transfusion. Methods and compositions for improved clinical outcomes for blood transfusions for cancer patients are also provided.

Methods for the storage of whole blood, and compositions thereof

Growing community of inventors

West Newton, MA, United States of America

Tatsuro Yoshida